1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoicacid, a,5-dihydroxy-a,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-,(aR,2S,5R,6R,8S)- cas no:78111-17-8

Name1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoicacid, a,5-dihydroxy-a,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-,(aR,2S,5R,6R,8S)-
CAS78111-17-8
Synonyms1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoicacid, a,5-dihydroxy-a,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-,(aR,2S,5R,6R,8S)- (9CI);Acanthifolicin, 9,10-deepithio-9,10-didehydro-; 1,7-Dioxaspiro[5.5]undecane,acanthifolicin deriv.; Spiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran],acanthifolicin deriv.; 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, a,5-dihydroxy-a,10-dimethyl-8-[1-methyl-3-[octahydro-8'-hydroxy-6'-[1-hydroxy-3-(3-methyl-1,7-dioxaspiro[5.5]undec-2-yl)butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-,[2'R-[2'a[R*[1R*[2S*(R*),5R*,6R*,8S*],2E]],4'ab,6'b[1S*,3S*(2S*,3R*,6S*)],8'a,8'aa]]-; NSC 677083; Okadaic acid
Molecular FormulaC44H68 O13
Molecular Weight805.00292

Appearancewhite crystals or powder
refractive index1.584
storage temp−20°C

Hazardclass6.1(a)

Hazard T: Toxic;
Risk R23/24/25
Safety

A poison by intraperitoneal route. Questionable carcinogen. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors.
Safety Information
Hazard Codes: T
T: Toxic
Risk Statements: 23/24/25-38
23/24/25: Toxic by inhalation, in contact with skin and if swallowed 
38: Irritating to the skin  
Safety Statements: 26-36/37-45
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37: Wear suitable protective clothing and gloves 
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)  
RIDADR: UN 3462 6.1/PG 1
WGK Germany: 3
RTECS: AA8227800
F10: Keep under argon.
HazardClass: 6.1(a)
PackingGroup: II

1.		sce-hmn-lym 3800 µmol/L		MUREAV    Mutation Research. 289 (1993),275.
2.		sce-hmn-ovr 2500 µmol/L		MUREAV    Mutation Research. 289 (1993),275.
3.		msc-ham-lng 10 µg/L		MUREAV    Mutation Research. 250 (1991),375.
4.		ipr-mus LD50:192 µg/kg		JACSAT    Journal of the American Chemical Society. 103 (1981),2469.