78246-49-8|Paroxetine hydrochlorideProducts Supply

Paroxetine hydrochloride cas no:78246-49-8

Synonyms: Piperidine,3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride,(3S,4R)- (9CI);(-)-trans-4-(4-Fluorophenyl)-3-(3,4-methylenedioxyphenoxymethyl)piperidinehydrochloride;Aropax 20;BRL 29060 hydrochloride;BRL 29060A;Deroxat;Paroxet;Paxil;Seroxat;Tagonis;Paroxetine Hcl;

Identification

NameParoxetine hydrochloride
CAS78246-49-8
SynonymsPiperidine,3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride,(3S,4R)- (9CI);(-)-trans-4-(4-Fluorophenyl)-3-(3,4-methylenedioxyphenoxymethyl)piperidinehydrochloride;Aropax 20;BRL 29060 hydrochloride;BRL 29060A;Deroxat;Paroxet;Paxil;Seroxat;Tagonis;Paroxetine Hcl;
Molecular FormulaC₁₉H₂₀FNO₃
Molecular Weight365.83

Chemical Properties

Appearancewhite or almost white crystalline powder
storage temp-20°C Freezer

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Safety

RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	625ug/kg (0.625mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: HEADACHE GASTROINTESTINAL: NAUSEA OR VOMITING	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 28(Suppl,
man	TDLo	oral	3654ug/kg/14D (3.654mg/kg)	BEHAVIORAL: WAKEFULNESS BEHAVIORAL: SLEEP BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 28(Suppl,
mouse	LD50	intravenous	42mg/kg (42mg/kg)	?	Acta Psychiatrica Scandinavica, Supplementum. Vol. 350, Pg. 31, 1989.
mouse	LD50	oral	378mg/kg (378mg/kg)	?	Acta Psychiatrica Scandinavica, Supplementum. Vol. 350, Pg. 31, 1989.
rat	LD50	intravenous	30mg/kg (30mg/kg)	?	Acta Psychiatrica Scandinavica, Supplementum. Vol. 350, Pg. 31, 1989.
rat	LD50	oral	415mg/kg (415mg/kg)	?	Acta Psychiatrica Scandinavica, Supplementum. Vol. 350, Pg. 31, 1989.
women	TDLo	oral	7400ug/kg/3W- (7.4mg/kg)	BEHAVIORAL: WAKEFULNESS BEHAVIORAL: TOXIC PSYCHOSIS BEHAVIORAL: AGGRESSION	Journal of the American Academy of Child and Adolescent Psychiatry. Vol. 36, Pg. 721, 1997.

supplier list

ZHEJIANG CHEMIALS IM & EXP CORP.: Tel:86-571-87048079; Address: No.37,Qingchun Road,Hangzhou,China

Luna Chemicals Co.,Ltd.: Tel:; Address: 1502-1503,No.310 North Zhong Shan Rd., Hangzhou,China

SUNWELL CHEMICALS CO.,LTD.(INTERPHARMA TRADING CO...: Tel:; Address: SUITE 1108,GOLDEN PLAZA,NO.118,QING CHUN ROAD,HANGZHOU,ZHEJIANG,CHINA

IFFECT CHEMPHAR CO., LTD.: Tel:86-25-84679300; Address: 509, FuXin International Building, No.359 HongWu R

SINOCHEM NINGBO LTD.: Tel:86-574-87260209 87348868; Address: 21 Jiangxia St.,Ningbo 315000 .Zhejiang. China

Maxpharm Group: Tel:; Address: B-24AB, Qingnian Plaza, Wuhan, 430022, China

Ancheng Pharma Limited: Tel:+86-755-82713308; Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China

ZunAn Commerce & Industrial Co., Ltd.: Tel:锛?86-755-82910159, 82910995,82910996; Address: Room 3007, United Plaza A, Binhe Road 5022, Shenzhen, P.R.China

CHONGQING TRUST LONG CO.,LTD.: Tel:; Address: 3-6-2, No.1, Xinglong Road, Longxi Town, Yubei Dist.,Chongqing,China

Taizhou Shengyu Chemical Co., Ltd.: Tel:; Address: Room 1308-1310, Ocean Plaza,Taizhou, ZheJiang, China

Sunasia Co., Ltd.: Tel:; Address: Suite 1503, 15Fl., Huijin Mansion, No. 77 He Yi Road, Ningbo 315000 China

Suzhou Chontech Pharmachem Technology Co.,Ltd.: Tel:+86-512-66561568; Address: 77 Jinfeng Road(M.),Suzhou, 215101 China

CIDIC Co.,Ltd.: Tel:; Address: 15/F, HODO International Plaza, 531 Zhongshan Road, Wuxi, China

Jiangxi Biochem Co., Ltd.: Tel:; Address: 1-6F, 118 Xinzhou road, Nanchang, Jiangxi, China

Chemfar Ltd.: Tel:; Address: 16E,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China

Paroxetine hydrochloride cas no:78246-49-8

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