78246-49-8|Paroxetine hydrochlorideProducts Supply

Paroxetine hydrochloride cas no:78246-49-8

Synonyms: Piperidine,3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride,(3S,4R)- (9CI);(-)-trans-4-(4-Fluorophenyl)-3-(3,4-methylenedioxyphenoxymethyl)piperidinehydrochloride;Aropax 20;BRL 29060 hydrochloride;BRL 29060A;Deroxat;Paroxet;Paxil;Seroxat;Tagonis;Paroxetine Hcl;

Identification

NameParoxetine hydrochloride
CAS78246-49-8
SynonymsPiperidine,3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride,(3S,4R)- (9CI);(-)-trans-4-(4-Fluorophenyl)-3-(3,4-methylenedioxyphenoxymethyl)piperidinehydrochloride;Aropax 20;BRL 29060 hydrochloride;BRL 29060A;Deroxat;Paroxet;Paxil;Seroxat;Tagonis;Paroxetine Hcl;
Molecular FormulaC₁₉H₂₀FNO₃
Molecular Weight365.83

Chemical Properties

Appearancewhite or almost white crystalline powder
storage temp-20°C Freezer

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Safety

RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	625ug/kg (0.625mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: HEADACHE GASTROINTESTINAL: NAUSEA OR VOMITING	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 28(Suppl,
man	TDLo	oral	3654ug/kg/14D (3.654mg/kg)	BEHAVIORAL: WAKEFULNESS BEHAVIORAL: SLEEP BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 28(Suppl,
mouse	LD50	intravenous	42mg/kg (42mg/kg)	?	Acta Psychiatrica Scandinavica, Supplementum. Vol. 350, Pg. 31, 1989.
mouse	LD50	oral	378mg/kg (378mg/kg)	?	Acta Psychiatrica Scandinavica, Supplementum. Vol. 350, Pg. 31, 1989.
rat	LD50	intravenous	30mg/kg (30mg/kg)	?	Acta Psychiatrica Scandinavica, Supplementum. Vol. 350, Pg. 31, 1989.
rat	LD50	oral	415mg/kg (415mg/kg)	?	Acta Psychiatrica Scandinavica, Supplementum. Vol. 350, Pg. 31, 1989.
women	TDLo	oral	7400ug/kg/3W- (7.4mg/kg)	BEHAVIORAL: WAKEFULNESS BEHAVIORAL: TOXIC PSYCHOSIS BEHAVIORAL: AGGRESSION	Journal of the American Academy of Child and Adolescent Psychiatry. Vol. 36, Pg. 721, 1997.

supplier list

Ancheng Pharma Limited: Tel:+86-755-82713308; Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China

CHONGQING TRUST LONG CO.,LTD.: Tel:; Address: 3-6-2, No.1, Xinglong Road, Longxi Town, Yubei Dist.,Chongqing,China

Taizhou Shengyu Chemical Co., Ltd.: Tel:; Address: Room 1308-1310, Ocean Plaza,Taizhou, ZheJiang, China

DANKONG INDUSTRY & TRADE GROUP CO.,LTD: Tel:; Address: NO.83 jiafang beilu jiaojiang,Zhejiang China

Zhejiang Chempharm Industry & Trading Co., Ltd.: Tel:0086-571-87701568 87701600; Address: 12,lianhuafeng road,yuhuangshan, Hangzhou,China

Fischer Chemicals AG: Tel:+41-44-389 69 69; Address: Riesbachstrasse 57 8034 Zurich, Switzerland

Leap Labchem Co.,Ltd: Tel:+86-(571)-87756549; Address: Zhongtian Mansion, No.173, Yugu Road Xihu District, Hangzhou 310007,

Qilong Chemical Co., Ltd.: Tel:86-574-63858500; Address: No.586, Jiangnan Road,High-tech Park, Ningbo, Zhejiang 315040,

Shanghai Zhongye Pharmaceutial & Chemical Co., Ltd.: Tel:+86-(21)-62038888, 62036888; Address: 13/G, ZhongXing Trade Building, 2020 ZhongShan Road (North), Shanghai 200063,

Shanghai Everchem Co., Ltd.: Tel:+86-(21)-51923949; Address: No.277 Zheqiao Road, Shanghai 201206,

Jiangxi Synergy Pharmaceuticals Co., Ltd.: Tel:+86-(795)-4605608,4605871; Address: Fengtian Road , Fengtian Industry Zone, Fengxin, Jiangxi 330700,

Zhejiang Ouhua Chemical Imp.& Exp. Co., Ltd.: Tel:+86-(576)-888-26569; Address: No.196 Hisun Avenue, Jiaojiang, Taizhou, Zhejiang 318000,

Huili Chemical Co., Ltd.: Tel:+86-(21)-58311983; Address: Century Avenue,Pudong New District, Shanghai, Shanghai 200122,

ACIC Fine Chemicals Inc.: Tel:+1-(800)-265-6727; Address: 11772 West Sample Road, Coral Springs, Florida 33065,

Jiangsu Zhongbang Pharmaceutical Co., Ltd.: Tel:+86-(25)-57887898, 57886700, 57886698; Address: 188 Shuangao Road , Gaochun Development Zone, Nanjing, Jiangsu 211300,

Paroxetine hydrochloride cas no:78246-49-8

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