78246-49-8|Paroxetine hydrochlorideProducts Supply

Paroxetine hydrochloride cas no:78246-49-8

Synonyms: Piperidine,3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride,(3S,4R)- (9CI);(-)-trans-4-(4-Fluorophenyl)-3-(3,4-methylenedioxyphenoxymethyl)piperidinehydrochloride;Aropax 20;BRL 29060 hydrochloride;BRL 29060A;Deroxat;Paroxet;Paxil;Seroxat;Tagonis;Paroxetine Hcl;

Identification

NameParoxetine hydrochloride
CAS78246-49-8
SynonymsPiperidine,3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-, hydrochloride,(3S,4R)- (9CI);(-)-trans-4-(4-Fluorophenyl)-3-(3,4-methylenedioxyphenoxymethyl)piperidinehydrochloride;Aropax 20;BRL 29060 hydrochloride;BRL 29060A;Deroxat;Paroxet;Paxil;Seroxat;Tagonis;Paroxetine Hcl;
Molecular FormulaC₁₉H₂₀FNO₃
Molecular Weight365.83

Chemical Properties

Appearancewhite or almost white crystalline powder
storage temp-20°C Freezer

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(b)

Safety Data

Safety

RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	625ug/kg (0.625mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: HEADACHE GASTROINTESTINAL: NAUSEA OR VOMITING	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 28(Suppl,
man	TDLo	oral	3654ug/kg/14D (3.654mg/kg)	BEHAVIORAL: WAKEFULNESS BEHAVIORAL: SLEEP BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 28(Suppl,
mouse	LD50	intravenous	42mg/kg (42mg/kg)	?	Acta Psychiatrica Scandinavica, Supplementum. Vol. 350, Pg. 31, 1989.
mouse	LD50	oral	378mg/kg (378mg/kg)	?	Acta Psychiatrica Scandinavica, Supplementum. Vol. 350, Pg. 31, 1989.
rat	LD50	intravenous	30mg/kg (30mg/kg)	?	Acta Psychiatrica Scandinavica, Supplementum. Vol. 350, Pg. 31, 1989.
rat	LD50	oral	415mg/kg (415mg/kg)	?	Acta Psychiatrica Scandinavica, Supplementum. Vol. 350, Pg. 31, 1989.
women	TDLo	oral	7400ug/kg/3W- (7.4mg/kg)	BEHAVIORAL: WAKEFULNESS BEHAVIORAL: TOXIC PSYCHOSIS BEHAVIORAL: AGGRESSION	Journal of the American Academy of Child and Adolescent Psychiatry. Vol. 36, Pg. 721, 1997.

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SUNWELL CHEMICALS CO.,LTD.(INTERPHARMA TRADING CO...: Tel:; Address: SUITE 1108,GOLDEN PLAZA,NO.118,QING CHUN ROAD,HANGZHOU,ZHEJIANG,CHINA

Hangzhou Rongda Pharm & Chem Co, Ltd.: Tel:0571-28889928; Address: Xinqiao Development Zone, Yuhang, Hangzhou, China

ZunAn Commerce & Industrial Co., Ltd.: Tel:锛?86-755-82910159, 82910995,82910996; Address: Room 3007, United Plaza A, Binhe Road 5022, Shenzhen, P.R.China

CHONGQING TRUST LONG CO.,LTD.: Tel:; Address: 3-6-2, No.1, Xinglong Road, Longxi Town, Yubei Dist.,Chongqing,China

Sunji & Co., Ltd.: Tel:86-755-8825 1355 /1365 /1379; Address: Room 2103-2104, Block C , Huangdu Plaza, 3008 Yitian Road, Shenzhen 518048, P.R. of China

Wuxi Guolian Import & Export Co., Ltd.: Tel:; Address: A.9/F. Hongdou International Plaza, 531 ZhongShan Road, Wuxi China

Fischer Chemicals AG: Tel:+41-44-389 69 69; Address: Riesbachstrasse 57 8034 Zurich, Switzerland

Hangzhou Chiral Medicine Chemical Co Ltd: Tel:+86-(571)-82623231, 82638910; Address: 288 South Shi Xin Road, XiaoShan, Hangzhou 311200,

Qilong Chemical Co., Ltd.: Tel:86-574-63858500; Address: No.586, Jiangnan Road,High-tech Park, Ningbo, Zhejiang 315040,

Aesica Pharmaceuticals Limited: Tel:+44-(1670)-590595; Address: Windmill Industrial Estate, Shotton Lane, Cramlington, Northumberland NE23 3JL,

Taizhou Shengyu Dyestuff Chemical Co.,Ltd.: Tel:+86-(576)-88861016, 88861026; Address: Room 1308-1310, Ocean Plaza, Taizhou, Zhejiang 318000,

Huili Chemical Co., Ltd.: Tel:+86-(21)-58311983; Address: Century Avenue,Pudong New District, Shanghai, Shanghai 200122,

Tecoland Corporation: Tel:+1-(732)-603-9577; Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428,

Chongqing Trust Long Co., Ltd.: Tel:+86-(23)-6760-5657, 6791-0421, 6707-4306; Address: 3-6-2, No.1, Xinglong Road, Longxi Town, Yubei Dist, Chongqing 401147,

Wuhan Borui Fine Chemical Co., Ltd.: Tel:+86-(27)-8355-0361; Address: No.448 Jinghan Road, QiaoKou, Wuhan, Hubei 430022,

Paroxetine hydrochloride cas no:78246-49-8

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