Terbinafine hydrochloride cas no:78628-80-5
Synonyms: Lamisil Krem;Terbinafina [Spanish];Terbinafien HCl;Terbinafine hydrochloride (Lamisil);(E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine hydrochloride;Terbinafine hydrochloride (JAN);Terbinafinum [Latin];SF 86-327 hydrochloride;(E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride;Terbinnafine HCL;1-Naphthalenemethanamine, N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-, (E)-, monohydrochloride;Terbinafine HCL(DMF) and its intermediates;Lamisil (TN);Lamisil;N-[(2E)-6,6-dimethyl-2-Hepten-4-yl]-N-methyl-1-naphthalenemethylamine hydrochloride;
NameTerbinafine hydrochloride
CAS78628-80-5
SynonymsLamisil Krem;Terbinafina [Spanish];Terbinafien HCl;Terbinafine hydrochloride (Lamisil);(E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine hydrochloride;Terbinafine hydrochloride (JAN);Terbinafinum [Latin];SF 86-327 hydrochloride;(E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride;Terbinnafine HCL;1-Naphthalenemethanamine, N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-, (E)-, monohydrochloride;Terbinafine HCL(DMF) and its intermediates;Lamisil (TN);Lamisil;N-[(2E)-6,6-dimethyl-2-Hepten-4-yl]-N-methyl-1-naphthalenemethylamine hydrochloride;
EINECS(EC#)245-385-8
Molecular FormulaC21H26ClN
Molecular Weight327.9
AppearanceCrystalline powder
refractive index1.586
storage temp-20°C Freezer
Hazard Xi: Irritant;N: Dangerous for the environment;
Risk R36/37/38
Safety
Hazard Codes?of Terbinafine Hcl (CAS NO.78628-80-5):?
Xi,
N
Risk Statements: 36/37/38-50/53?
R36/37/38: Irritating to eyes, respiratory system and skin.?
R50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: 26-36/37/39-61-60?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.?
S61: Avoid release to the environment. Refer to special instructions / safety data sheets.?
S60: This material and its container must be disposed of as hazardous waste.
RIDADR:?UN 3077 9/PG 3
?
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
subcutaneous |
> 2gm/kg (2000mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: ATAXIA
BLOOD: CHANGES IN SPLEEN |
Kiso to Rinsho. Clinical Report. Vol. 24, Pg. 7888, 1990. |
| rat |
LD50 |
skin |
> 2gm/kg (2000mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BEHAVIORAL: ATAXIA
BLOOD: CHANGES IN SPLEEN |
Kiso to Rinsho. Clinical Report. Vol. 24, Pg. 7922, 1990. |
| rat |
LD50 |
subcutaneous |
> 2gm/kg (2000mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
BLOOD: CHANGES IN SPLEEN
BEHAVIORAL: ATAXIA |
Kiso to Rinsho. Clinical Report. Vol. 24, Pg. 7922, 1990. |
| women |
TDLo |
oral |
210mg/kg/6W-I (210mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: CHANGE IN FUNCTION: TASTE |
Lancet. Vol. 339, Pg. 1483, 1992. |
