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Methyl acetate cas no:79-20-9

Synonyms: Acetic acid methyl ester

Identification
NameMethyl acetate
CAS79-20-9
SynonymsAcetic acid methyl ester
EINECS(EC#)201-185-2
Molecular FormulaC3H6O2
Molecular Weight74.08
Chemical Properties
AppearanceClear liquid
refractive index1.36-1.362
storage tempFlammables area
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass3
Safety Data

Hazard F:Flammable
Risk R11;R36;R66;R67
Safety

Moderately toxic by several routes. A human systemic irritant by inhalation. A moderate skin and eye irritant. Mutation data reported. Dangerous fire hazard when exposed to heat, flame, or oxidizers. Moderate explosion hazard when exposed to heat or flame. When heated to decomposition it emits acrid smoke and fumes. See also ESTERS.
Hazard Codes of Methyl acetate (CAS NO.79-20-9): FlammableF,IrritantXi
Risk Statements: 11-36-66-67
R11: Highly flammable.?
R36: Irritating to eyes.?
R66: Repeated exposure may cause skin dryness or cracking.?
R67: Vapours may cause drowsiness and dizziness.
Safety Statements: 16-26-29-33
S16: Keep away from sources of ignition.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S29: Do not empty into drains.?
S33: Take precautionary measures against static discharges.
RIDADR: UN 1231 3/PG 2
WGK Germany: 1
RTECS: AI9100000
HazardClass: 3
PackingGroup: II


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LCLo inhalation 67gm/m3/1H (67000mg/m3) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 5, Pg. 1, 1933.
cat LDLo subcutaneous 3gm/kg (3000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: ATAXIA
Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 5, Pg. 1, 1933.
guinea pig LD50 skin > 20mL/kg (20mL/kg) ? National Technical Information Service. Vol. OTS0556681,
guinea pig LDLo subcutaneous 3gm/kg (3000mg/kg) ? Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 5, Pg. 1, 1933.
human TCLo inhalation 15000mg/m3 (15000mg/m3) SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

LUNGS, THORAX, OR RESPIRATION: COUGH

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 5, Pg. 1, 1933.
mammal (species unspecified) LD50 unreported 214mg/kg (214mg/kg) ? Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(8), Pg. 107, 1968.
mouse LCLo inhalation 34gm/m3/4H (34000mg/m3) BEHAVIORAL: GENERAL ANESTHETIC Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 5, Pg. 1, 1933.
rabbit LD50 intraduodenal 3700mg/kg (3700mg/kg) ? Food and Cosmetics Toxicology. Vol. 17, Pg. 859, 1979.
rabbit LD50 oral 3705mg/kg (3705mg/kg) ? Industrial Medicine and Surgery. Vol. 41, Pg. 31, 1972.
rabbit LD50 skin > 5gm/kg (5000mg/kg) ? Food and Cosmetics Toxicology. Vol. 17, Pg. 859, 1979.
rat LCLo inhalation 32000ppm/4H (32000ppm) ? American Industrial Hygiene Association Journal. Vol. 23, Pg. 95, 1962.
rat LD50 oral > 5gm/kg (5000mg/kg) ? Food and Cosmetics Toxicology. Vol. 17, Pg. 859, 1979.
rat LDLo subcutaneous 8gm/kg (8000mg/kg) ? Bolletino della Societe Italiana di Biologia Sperimentale. Vol. 18, Pg. 45, 1943.

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