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2-Nitropropane cas no:79-46-9

Synonyms: -

Identification
Name2-Nitropropane
CAS79-46-9
Synonyms-
EINECS(EC#)201-209-1
Molecular FormulaC3H7NO2
Molecular Weight89.09
Chemical Properties
Appearanceliquid
refractive index1.393-1.395
storage tempFlammables area
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass3.2
Safety Data

Hazard T:Toxic;
Risk R10;R20/22;R45
Safety

Confirmed carcinogen with experimental carcinogenic, tumorigenic, and teratogenic data. Poison by intraperitoneal route. Moderately toxic by ingestion and inhalation. Human systemic effects by inhalation: anorexia, hypermotility, diarrhea, nausea or vomiting. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. Can cause liver and kidney injury, methemoglobinemia, and cyanosis. Very dangerous fire hazard when exposed to heat, open flame, or oxidizers. May explode on heating. Violent reactions with chlorosulfonic acid, oleum. May react with amines + heavy metal oxides (e.g., mercury oxide or silver oxide) to form explosive salts. May ignite on contact with mixtures of carbon + hopcalite, which are used in some respirators. Hopcalite is a catalyst consisting of coprecipitated copper(II) oxide and manganese(IV) oxide. To fight fire, use alcohol foam, CO2, dry chemical, water spray. When heated to decomposition it emits toxic fumes of NOx.
Hazard Codes:
ToxicT
Risk Statements:
R45:May cause cancer. 
R10:Flammable. 
R20/22:Harmful by inhalation and if swallowed.
Safety Statements:
S53:Avoid exposure - obtain special instructions before use. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2608 3/PG 3
WGK Germany: 3
RTECS: TZ5250000
HazardClass: 3.2
PackingGroup: III
HS Code: 29042000


HS Code 29042000

Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LCLo inhalation 714ppm/5H (714ppm) sense organs and special senses: lacrimation: eye lungs, thorax, or respiration: dyspnea gastrointestinal: changes in structure or function of salivary glands AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 5, Pg. 52, 1952.
guinea pig LCLo inhalation 4622ppm/5H (4622ppm) behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: dyspnea lungs, thorax, or respiration: cyanosis AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 5, Pg. 52, 1952.
man TCLo inhalation 20ppm (20ppm) behavioral: anorexia (human gastrointestinal: "hypermotility, diarrhea" gastrointestinal: nausea or vomiting Industrial Medicine. Vol. 16, Pg. 441, 1947.
mouse LC50 inhalation 10gm/m3/2H (10000mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 94, 1982.
mouse LD50 intraperitoneal 75mg/kg (75mg/kg)   National Technical Information Service. Vol. AD691-490,
rabbit LCLo inhalation 2381ppm/5H (2381ppm) behavioral: convulsions or effect on seizure threshold lungs, thorax, or respiration: cyanosis lungs, thorax, or respiration: dyspnea AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 5, Pg. 52, 1952.
rabbit LDLo oral 500mg/kg (500mg/kg) behavioral: somnolence (general depressed activity) lungs, thorax, or respiration: respiratory stimulation behavioral: ataxia Journal of Industrial Hygiene and Toxicology. Vol. 22, Pg. 315, 1940.
rat LC50 inhalation 400ppm/6H (400ppm)   Journal of Environmental Pathology and Toxicology. Vol. 2(5), Pg. 233, 1979.
rat LD50 oral 720mg/kg (720mg/kg)   "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 430, 1969.
rat LDLo intraperitoneal 1100mg/kg (1100mg/kg) blood: methemoglobinemia-carboxyhemoglobin Bulletin de la Societe de Pharmacie de Lille. Vol. (2), Pg. 83, 1972.

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Chem Service, Inc
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