Octreotide cas no:79517-01-4
Synonyms: L-Cysteinamide,D-phenylalanyl-L-cysteinyl-Lphenylalanyl- D-tryptophyl-L-lysyl-Lthreonyl- N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl) propyl]-,cyclic (2f7)-disulfide,acetate (salt);Sandostatin (TN);Octreotide acetate (JAN);Sandostatin LAR;acetic acid; 10-(4-aminobutyl)-19-[(2-amino-3-phenyl-propanoyl)amino]-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide;Sandostatin;SMS 201-995;
NameOctreotide
CAS79517-01-4
SynonymsL-Cysteinamide,D-phenylalanyl-L-cysteinyl-Lphenylalanyl- D-tryptophyl-L-lysyl-Lthreonyl- N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl) propyl]-,cyclic (2f7)-disulfide,acetate (salt);Sandostatin (TN);Octreotide acetate (JAN);Sandostatin LAR;acetic acid; 10-(4-aminobutyl)-19-[(2-amino-3-phenyl-propanoyl)amino]-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide;Sandostatin;SMS 201-995;
Molecular FormulaC49H66N10O10S2
Molecular Weight1019.23934
AppearanceColourless to off-white lyophilised solid
storage temp−20°C
Safety
A poison by subcutaneous and intravenous routes. Human systemic effects: changes in structure or function of endocrine pancreas, liver function tests impaired. When heated to decomposition it emits toxic vapors of NOx and SOx.
WGK Germany: 3
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scu-man TDLo:2587 µg/kg:GIT,LVR
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LANCAO Lancet. 348 (1996),1668. |
| 2. |
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scu-man TDLo:1429 µg/kg:GIT,LVR
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LANCAO Lancet. 348 (1996),1668. |
| 3. |
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scu-rat LD:>50 mg/kg
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KSRNAM Kiso to Rinsho. Clinical Report. 21 (1987),5151. |
| 4. |
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ivn-rat LD50:18,100 µg/kg
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IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 22 (1991),967. |
| 5. |
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scu-mus LD:>100 mg/kg
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KSRNAM Kiso to Rinsho. Clinical Report. 21 (1987),5151. |
| 6. |
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ivn-mus LD50:72300 µg/kg
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IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 22 (1991),967. |
