79617-96-2|1-Naphthalenamine,4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, (1S,4S)-Products Supply

1-Naphthalenamine,4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, (1S,4S)- cas no:79617-96-2

Synonyms: 1-Naphthalenamine,4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, (1S-cis)-;(+)-Sertraline;(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine;CP 51974;

Identification

Name1-Naphthalenamine,4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, (1S,4S)-
CAS79617-96-2
Synonyms1-Naphthalenamine,4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, (1S-cis)-;(+)-Sertraline;(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine;CP 51974;
Molecular FormulaC₁₇H₁₇Cl₂N
Molecular Weight306.23

Chemical Properties

Appearancewhite to off-white powder

Safety Data

Hazard UN NO.
Risk R36/37/38
Safety

Hazard Codes of Sertraline (CAS NO.79617-96-2): Xi
Risk Statements:
36:?Irritating to the eyes
37:?Irritating to the respiratory system
38:?Irritating to the skin
Safety Statements:
26:?In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:?Wear suitable protective clothing

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	oral	5714ug/kg/9D- (5.714mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: EXCITEMENT	Journal of Clinical Psychiatry. Vol. 55, Pg. 316, 1994.
man	TDLo	oral	3571mg/kg/5D- (3571mg/kg)	ENDOCRINE: ANTIDIURESIS	American Journal of Psychiatry. Vol. 152, Pg. 809, 1995.
women	TDLo	oral	2mg/kg/2D-I (2mg/kg)	BEHAVIORAL: EXCITEMENT	Journal of the American Academy of Child and Adolescent Psychiatry. Vol. 35, Pg. 975, 1996.
women	TDLo	oral	6mg/kg/4D-I (6mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" ENDOCRINE: ANTIDIURESIS	American Journal of Psychiatry. Vol. 152, Pg. 809, 1995.
women	TDLo	oral	10500ug/kg/3W (10.5mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) ENDOCRINE: ANTIDIURESIS	Annals of Internal Medicine. Vol. 123, Pg. 811, 1995.
women	TDLo	oral	28mg/kg/4W-I (28mg/kg)	BLOOD: AGRANULOCYTOSIS	Postgraduate Medical Journal. Vol. 72, Pg. 446, 1996.
women	TDLo	oral	63mg/kg/10W-I (63mg/kg)	BLOOD: TUMORS	American Journal of Psychiatry. Vol. 153, Pg. 443, 1996.
women	TDLo	oral	70mg/kg/7W-I (70mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	American Journal of Psychiatry. Vol. 153, Pg. 732, 1996.

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1-Naphthalenamine,4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-, (1S,4S)- cas no:79617-96-2

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