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Bisphenol A cas no:80-05-7

Synonyms: 4,4'-(propane-2,2-diyl)diphenol;p,p'-isopropylidenebisphenol;BPA;4,4'-(1-Methylethylidene)bisphenol;2,2-(4,4'-Dihydroxydiphenyl)propane;2,2-Bis(4-hydroxyphenyl)propane;4,4'-Bisphenol A;4,4'-Isopropylidenediphenol;2,2-Di(4-phenylol)propane;

Identification
NameBisphenol A
CAS80-05-7
Synonyms4,4'-(propane-2,2-diyl)diphenol;p,p'-isopropylidenebisphenol;BPA;4,4'-(1-Methylethylidene)bisphenol;2,2-(4,4'-Dihydroxydiphenyl)propane;2,2-Bis(4-hydroxyphenyl)propane;4,4'-Bisphenol A;4,4'-Isopropylidenediphenol;2,2-Di(4-phenylol)propane;
EINECS(EC#)201-245-8
Molecular FormulaC15H16O2
Molecular Weight228.29
Chemical Properties
AppearanceWhite to light brown flakes or powder
Safety Data

Hazard Xn:Harmful
Risk R37;R41;R43;R62
Safety

Safety Information about?Bisphenol A (CAS NO.80-05-7):
Hazard Codes: Xn
Risk Statements: 37-41-43-62
37:?Irritating to the respiratory system?
41:?Risk of serious damage to eyes?
43:?May cause sensitization by skin contact?
62:?Possible risk of impaired fertility?
Safety Statements:?26-36/37/39-45-46
26:?In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
36/37/39:?Wear suitable protective clothing, gloves and eye/face protection?
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)?
46:?If swallowed, seek medical advice immediately and show this container or label?
RTECS:? SL6300000
HS Code:? 29072300
Poison by intraperitoneal route. Moderately toxic by ingestion, inhalation, and skin contact. Experimental teratogenic and reproductive effects. A skin and eye irritant. When heated to decomposition it emits acrid and irritating fumes.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 4gm/kg (4000mg/kg) AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(7), Pg. 25, 1968.
mammal (species unspecified) LD50 oral 6500mg/kg (6500mg/kg) ? "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 135, 1969.
mouse LC inhalation > 1700mg/m3/2H (1700mg/m3) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 2, Pg. 50, 1961.
mouse LD50 intraperitoneal 150mg/kg (150mg/kg) ? National Technical Information Service. Vol. AD691-490,
mouse LD50 oral 2400mg/kg (2400mg/kg) AUTONOMIC NERVOUS SYSTEM: OTHER (DIRECT) PARASYMPATHOMIMETIC

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(7), Pg. 25, 1968.
mouse LDLo subcutaneous 2500mg/kg (2500mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LIVER: FATTY LIVER DEGERATION
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 2, Pg. 50, 1961.
rabbit LD50 oral 2230mg/kg (2230mg/kg) ? American Industrial Hygiene Association Journal. Vol. 28, Pg. 301, 1967.
rabbit LD50 skin 3mL/kg (3mL/kg) ? AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.
rat LD50 oral 3250mg/kg (3250mg/kg) ? American Industrial Hygiene Association Journal. Vol. 28, Pg. 301, 1967.

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