2-Propenoic acid,2-chloro-, methyl ester cas no:80-63-7

Name2-Propenoic acid,2-chloro-, methyl ester
CAS80-63-7
SynonymsAcrylicacid, 2-chloro-, methyl ester (6CI,7CI,8CI); 2-Chloroacrylic acid methyl ester;Methyl 2-chloro-2-propenoate; Methyl 2-chloroacrylate; Methyl2-chloropropenoate; Methyl a-chloroacrylate; NSC 32608
EINECS(EC#)201-298-7
Molecular FormulaC4H5 Cl O2
Molecular Weight120.54

refractive index1.426
storage temp0-6°C

Hazardclass6.1(a)

Hazard T+
Risk 34-26-24/25-10
Safety

Moderately toxic by inhalation. Human systemic effects by inhalation: conjunctiva irritation. A severe skin irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl⁻. See also ESTERS.
Safety Information of Methyl-2-chloroacrylate (CAS NO.80-63-7):
Hazard Codes: T+
Risk Statements: 34-26-24/25-10 
10:  Flammable
24:  Toxic in contact with skin 
25:  Toxic if swallowed 
26:  Very Toxic by inhalation 
34:  Causes burns
Safety Statements: 45-38-36/37/39-26-16
16:  Keep away from sources of ignition - No smoking
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:  Wear suitable protective clothing  
37:  Wear suitable gloves 
38:  In case of insufficient ventilation, wear suitable respiratory equipment 
39:  Wear eye/face protection 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LC50	inhalation	500mg/m3/2H (500mg/m3)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Farmakologiya i Toksikologiya Vol. 19, Pg. 60, 1956.
guinea pig	LC50	inhalation	500mg/m3/2H (500mg/m3)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Farmakologiya i Toksikologiya Vol. 19, Pg. 60, 1956.
human	TCLo	inhalation	5ppm (5ppm)	SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE	"Practical Toxicology of Plastics," Lefaux, R., Cleveland, OH, Chemical Rubber Co., 1968Vol. -, Pg. 90, 1968.
mouse	LC50	inhalation	500mg/m3/2H (500mg/m3)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Farmakologiya i Toksikologiya Vol. 19, Pg. 60, 1956.
rabbit	LC50	inhalation	500mg/m3/2H (500mg/m3)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	Farmakologiya i Toksikologiya Vol. 19, Pg. 60, 1956.
rabbit	LD50	skin	270mg/kg (270mg/kg)	LUNGS, THORAX, OR RESPIRATION: FIBROSING ALVEOLITIS KIDNEY, URETER, AND BLADDER: CHANGES IN BOTH TUBULES AND GLOMERULI LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL"	National Technical Information Service. Vol. OTS0535234,
rat	LC50	inhalation	500mg/m3/2H (500mg/m3)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Farmakologiya i Toksikologiya Vol. 19, Pg. 60, 1956.
rat	LD50	intraperitoneal	27mg/kg (27mg/kg)	LUNGS, THORAX, OR RESPIRATION: FIBROSING ALVEOLITIS KIDNEY, URETER, AND BLADDER: CHANGES IN BOTH TUBULES AND GLOMERULI LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL"	National Technical Information Service. Vol. OTS0535234,
rat	LD50	oral	68mg/kg (68mg/kg)	LUNGS, THORAX, OR RESPIRATION: FIBROSING ALVEOLITIS LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL" KIDNEY, URETER, AND BLADDER: CHANGES IN BOTH TUBULES AND GLOMERULI	National Technical Information Service. Vol. OTS0535234