THEOPHYLLINE SODIUM ACETATE cas no:8002-89-9

NameTHEOPHYLLINE SODIUM ACETATE
CAS8002-89-9
SynonymsTHEOPHYLLINE SODIUM ACETATE;THEOPHYLLOL;aceticacid,sodiumsalt,compd.withtheophylline(1:1);aceticacid,sodiumsalt,mixt.with3,7-dihydro-1,3-dimethyl-1h-purine-2,6-d;acet-theocinsodium;ionesodiumsalt;theocinsoluble;theophylline,compd.withsodiumacetate(1:1)
Molecular FormulaC₇H₈N₄O₂•C₂H₄O₂•Na
Molecular Weight263.24

Safety

Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. When heated to decomposition it emits toxic fumes of NO_x and Na₂O. See also THEOPHYLLINE.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
guinea pig	LD50	oral	205mg/kg (205mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 230, Pg. 194, 1957.
guinea pig	LD50	subcutaneous	180mg/kg (180mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 230, Pg. 194, 1957.
mouse	LD50	intraperitoneal	184mg/kg (184mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Acta Pharmaceutica Jugoslavica. Vol. 24, Pg. 89, 1974.
mouse	LD50	intravenous	257mg/kg (257mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 230, Pg. 194, 1957.
mouse	LD50	subcutaneous	286mg/kg (286mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE BEHAVIORAL: TETANY LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 197, Pg. 193, 1941.
rat	LD50	intravenous	311mg/kg (311mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 230, Pg. 194, 1957.
rat	LD50	oral	583mg/kg (583mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 230, Pg. 194, 1957.
rat	LD50	subcutaneous	188mg/kg (188mg/kg)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 230, Pg. 194, 1957.