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Safety
Moderately toxic by intravenous route. Human systemic effects: coma, convulsions, excitement, liver function tests impaired, muscle weakness, nausea or vomiting, visual field changes. Human teratogenic effects by ingestion include these developmental abnormalities: extra embryonic structures, homeostasis, reduced viability and other neonatal effects. Other experimental reproductive effects. When heated to decomposition it emits acrid smoke and fumes. See other camphor entries.
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| man | TDLo | oral | 843uL/kg (0.843mL/kg) | SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING |
Clinical Toxicology. Vol. 11, Pg. 151, 1977. |
| mouse | LD50 | intravenous | 1600mg/kg (1600mg/kg) | Therapie. Vol. 20, Pg. 321, 1965. | |
| women | TDLo | oral | 1180uL/kg (1.18mL/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT LIVER: LIVER FUNCTION TESTS IMPAIRED |
Clinical Toxicology. Vol. 11, Pg. 151, 1977. |
| women | TDLo | oral | 100mg/kg (100mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: NAUSEA OR VOMITING BLOOD: OTHER HEMOLYSIS WITH OR WITHOUT ANEMIA |
Postgraduate Medical Journal. Vol. 57, Pg. 725, 1981. |
| women | TDLo | oral | 148mg/kg (148mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: MUSCLE WEAKNESS GASTROINTESTINAL: NAUSEA OR VOMITING |
Pediatrics. Vol. 52, Pg. 713, 1973. |
| women | TDLo | unreported | 900mg/kg (900mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: COMA GASTROINTESTINAL: NAUSEA OR VOMITING |
Journal of the Florida Medical Association. Vol. 43, Pg. 999, 1957. |
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