Mercurophylline cas no:8012-34-8

NameMercurophylline
CAS8012-34-8
Synonymsmercupurin;mercurin;mercuzan;mercuzanthin;merthylline;mixturewiththeophylline;novurit;novurite
Molecular FormulaC14H24HgNO5 . C7H8N4O2 . Na
Molecular Weight487.94

Safety

Poison by subcutaneous, intraperitoneal, and intravenous routes. Human systemic effects by intravenous route: cardiac arrythmias. When Mercurophylline (CAS NO.8012-34-8) is heated to decomposition, it emits toxic fumes of Hg. See also MERCURY COMPOUNDS, INORGANIC; MERCURY COMPOUNDS, ORGANIC.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LDLo	intravenous	250mg/kg (250mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 99, Pg. 149, 1950.
human	TDLo	intravenous	28mg/kg (28mg/kg)	CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)	JAMA, Journal of the American Medical Association. Vol. 117, Pg. 1806, 1941.
mouse	LD50	intravenous	1410mg/kg (1410mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 99, Pg. 149, 1950.
mouse	LD50	subcutaneous	163mg(Hg)/kg (163mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 105, Pg. 336, 1952.
rabbit	LDLo	intravenous	177mg/kg (177mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 99, Pg. 149, 1950.
rat	LD50	intraperitoneal	121mg/kg (121mg/kg)		Therapie. Vol. 10, Pg. 936, 1955.