Aminopyrine-barbital cas no:8015-18-7

Synonyms: 5,5-diethyl-1,3-diazinane-2,4,6-trione: 4-dimethylamino-1,5-dimethyl-2 -phenyl-pyrazol-3-one;Veramid;PYRABITAL

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Identification
Safety Data
Toxicity

Identification

NameAminopyrine-barbital
CAS8015-18-7
Synonyms5,5-diethyl-1,3-diazinane-2,4,6-trione: 4-dimethylamino-1,5-dimethyl-2 -phenyl-pyrazol-3-one;Veramid;PYRABITAL
Molecular FormulaC13H17N3O . C8H12N2O3
Molecular Weight415.491

Safety Data

Safety

Moderately toxic by ingestion and other routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x.

Toxicity

1.	scu-mus TDLo:900 mg/kg (9-11D preg):TER	TXCYAC Toxicology. 29 (1984),281.
2.	ipr-rat TDLo:400 mg/kg (1D male):REP	KSRNAM Kiso to Rinsho. Clinical Report. 14 (1980),723.
3.	ipr-rat LD50:476 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 16 (1978),229.
4.	orl-mus LD50:1466 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 8 (1974),453.
5.	ipr-mus LD50:450 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 16 (1978),229.
6.	orl-mky LDLo:1 g/kg	HBAMAK Abdernalden’s Handbuch der Biologischen Arbeitsmethoden. 4 (1935),1289.
7.	orl-rbt LDLo:1200 mg/kg	HBAMAK Abdernalden’s Handbuch der Biologischen Arbeitsmethoden. 4 (1935),1289.

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