80382-23-6|Loxoprofen sodiumProducts Supply - Chemical intermediates Network

Loxoprofen sodium cas no:80382-23-6

Synonyms: Benzeneaceticacid, a-methyl-4-[(2-oxocyclopentyl)methyl]-,sodium salt (9CI);CS 600;CS 600 (antiinflammatory);Loxonin;Loxoprofensodium;Sodium 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionate;Sodiumloxoprofen;

Identification

NameLoxoprofen sodium
CAS80382-23-6
SynonymsBenzeneaceticacid, a-methyl-4-[(2-oxocyclopentyl)methyl]-,sodium salt (9CI);CS 600;CS 600 (antiinflammatory);Loxonin;Loxoprofensodium;Sodium 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionate;Sodiumloxoprofen;
EINECS(EC#)安全数据
Molecular FormulaC₁₅H₂₁NaO₅
Molecular Weight304.32

Safety Data

Safety Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Na2O.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	LDLo	oral	857ug/kg (0.857mg/kg)	LUNGS, THORAX, OR RESPIRATION: BRONCHIOLAR CONSTRICTION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of Toxicology, Clinical Toxicology. Vol. 31, Pg. 333, 1993.
mouse	LD50	intraperitoneal	1020mg/kg (1020mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE	Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories. Vol. 36, Pg. 1, 1984.
mouse	LD50	intravenous	740mg/kg (740mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE	Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories. Vol. 36, Pg. 1, 1984.
mouse	LD50	oral	3030mg/kg (3030mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE	Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories. Vol. 36, Pg. 1, 1984.
mouse	LD50	subcutaneous	1070mg/kg (1070mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE	Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories. Vol. 36, Pg. 1, 1984.
rat	LD50	intraperitoneal	245mg/kg (245mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE	Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories. Vol. 36, Pg. 1, 1984.
rat	LD50	intravenous	155mg/kg (155mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE	Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories. Vol. 36, Pg. 1, 1984.
rat	LD50	oral	145mg/kg (145mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE	Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories. Vol. 36, Pg. 1, 1984.
rat	LD50	subcutaneous	285mg/kg (285mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE	Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories. Vol. 36, Pg. 1, 1984.

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Loxoprofen sodium cas no:80382-23-6

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