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Loxoprofen sodium cas no:80382-23-6

Synonyms: Benzeneaceticacid, a-methyl-4-[(2-oxocyclopentyl)methyl]-,sodium salt (9CI);CS 600;CS 600 (antiinflammatory);Loxonin;Loxoprofensodium;Sodium 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionate;Sodiumloxoprofen;

Identification
NameLoxoprofen sodium
CAS80382-23-6
SynonymsBenzeneaceticacid, a-methyl-4-[(2-oxocyclopentyl)methyl]-,sodium salt (9CI);CS 600;CS 600 (antiinflammatory);Loxonin;Loxoprofensodium;Sodium 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionate;Sodiumloxoprofen;
EINECS(EC#)安全数据
Molecular FormulaC15H21NaO5
Molecular Weight304.32
Safety Data

Safety Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of Na2O.

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man LDLo oral 857ug/kg (0.857mg/kg) LUNGS, THORAX, OR RESPIRATION: BRONCHIOLAR CONSTRICTION

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Toxicology, Clinical Toxicology. Vol. 31, Pg. 333, 1993.
mouse LD50 intraperitoneal 1020mg/kg (1020mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories. Vol. 36, Pg. 1, 1984.
mouse LD50 intravenous 740mg/kg (740mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories. Vol. 36, Pg. 1, 1984.
mouse LD50 oral 3030mg/kg (3030mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories. Vol. 36, Pg. 1, 1984.
mouse LD50 subcutaneous 1070mg/kg (1070mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories. Vol. 36, Pg. 1, 1984.
rat LD50 intraperitoneal 245mg/kg (245mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories. Vol. 36, Pg. 1, 1984.
rat LD50 intravenous 155mg/kg (155mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories. Vol. 36, Pg. 1, 1984.
rat LD50 oral 145mg/kg (145mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories. Vol. 36, Pg. 1, 1984.
rat LD50 subcutaneous 285mg/kg (285mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
Sankyo Kenkyusho Nempo. Annual Report of Sankyo Research Laboratories. Vol. 36, Pg. 1, 1984.

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