804-63-7|Quinine sulphateProducts Supply - Chemical intermediates Network

Quinine sulphate cas no:804-63-7

Synonyms: Quinine, sulfate (2:1) (salt) (8CI);130-95-0;QUININE;Legatrin;Quinine, sulfate (2:1) (salt);Quine;Biquinate (*Bisulfate heptathydrate*);QUININE SULFATE (2:1);Coco-Quinine;Quinine bisulfate;(8.alpha.,9R)-6-Methoxycinchonan-9-ol;(R)-[(4S,5S,7S)-5-ethenyl-1-azabicyclo[2.2.2]oct-7-yl]-(6-methoxyquinolin-4-yl)methanol;Quinine sulfate (VAN);Quinamm;Cinchonan-9-ol, 6-methoxy-, (8.alpha.,9R)-, sulfate;Aflukin;Quinine sulfate anhydrous;Quinsan (*2:1 Sulfate salt*), dihydrate;Quinine sulfate anhydrous [USAN];Quine (*2:1 Sulfate salt*, dihydrate);Cinchonan-9-ol,6'-methoxy-,(8R,9R)-,sulfate (2:1) (salt);Quinamm (*2:1 Sulfate salt*), dihydrate;Quinine hydrogen sulfate;Cinchonan-9-ol, 6-methoxy-, (8.alpha.,9R)-, sulfate (2:1) (salt);Dentojel (*Bisulfate heptathydrate*);(R)-[(5S,7S)-5-ethenyl-1-azabicyclo[2.2.2]oct-7-yl]-(6-methoxyquinolin-4-yl)methanol; sulfuric acid;Quinine, sulfate;Cinchonan-9-ol, 6-methoxy-, (8alpha,9R)-, sulfate (2:1) (salt);Quinoline alkaloid;

Identification

NameQuinine sulphate
CAS804-63-7
SynonymsQuinine, sulfate (2:1) (salt) (8CI);130-95-0;QUININE;Legatrin;Quinine, sulfate (2:1) (salt);Quine;Biquinate (*Bisulfate heptathydrate*);QUININE SULFATE (2:1);Coco-Quinine;Quinine bisulfate;(8.alpha.,9R)-6-Methoxycinchonan-9-ol;(R)-[(4S,5S,7S)-5-ethenyl-1-azabicyclo[2.2.2]oct-7-yl]-(6-methoxyquinolin-4-yl)methanol;Quinine sulfate (VAN);Quinamm;Cinchonan-9-ol, 6-methoxy-, (8.alpha.,9R)-, sulfate;Aflukin;Quinine sulfate anhydrous;Quinsan (*2:1 Sulfate salt*), dihydrate;Quinine sulfate anhydrous [USAN];Quine (*2:1 Sulfate salt*, dihydrate);Cinchonan-9-ol,6'-methoxy-,(8R,9R)-,sulfate (2:1) (salt);Quinamm (*2:1 Sulfate salt*), dihydrate;Quinine hydrogen sulfate;Cinchonan-9-ol, 6-methoxy-, (8.alpha.,9R)-, sulfate (2:1) (salt);Dentojel (*Bisulfate heptathydrate*);(R)-[(5S,7S)-5-ethenyl-1-azabicyclo[2.2.2]oct-7-yl]-(6-methoxyquinolin-4-yl)methanol; sulfuric acid;Quinine, sulfate;Cinchonan-9-ol, 6-methoxy-, (8alpha,9R)-, sulfate (2:1) (salt);Quinoline alkaloid;
EINECS(EC#)212-359-2
Molecular FormulaC₄₀H₅₀N₄O₈S
Molecular Weight422.49

Safety Data

Safety

RIDADR: 1544
HazardClass: 6.1(b)
PackingGroup: III

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
human	TDLo	oral	4300ug/kg (4.3mg/kg)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BLOOD: AGRANULOCYTOSIS	British Medical Journal. Vol. 1, Pg. 605, 1977.
man	TDLo	oral	27mg/kg (27mg/kg)	SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE SENSE ORGANS AND SPECIAL SENSES: TINNITUS: EAR GASTROINTESTINAL: NAUSEA OR VOMITING	British Medical Journal. Vol. 287, Pg. 1700, 1983.
man	TDLo	oral	129mg/kg (129mg/kg)	SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE	Human Toxicology. Vol. 3, Pg. 399, 1984.
mouse	LDLo	oral	800mg/kg (800mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 78, Pg. 159, 1943.
women	LDLo	oral	126mg/kg/3W-I (126mg/kg)	CARDIAC: CARDIOMYOPATHY INCLUDING INFARCTION SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE"	British Journal of Clinical Practice. Vol. 46, Pg. 138, 1992.
women	LDLo	oral	220mg/kg (220mg/kg)	CARDIAC: OTHER CHANGES BLOOD: CHANGES IN SPLEEN LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA	Clinical Toxicology. Vol. 7, Pg. 129, 1974.
women	TDLo	oral	6500ug/kg (6.5mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS	American Journal of Kidney Diseases. Vol. 24, Pg. 211, 1994.
women	TDLo	oral	12mg/kg/1D-I (12mg/kg)	LIVER: "HEPATITIS, FIBROUS (CIRRHOSIS, POST-NECROTIC SCARRING)"	British Medical Journal. Vol. 286, Pg. 264, 1983.
women	TDLo	oral	45455ug/kg (45.455mg/kg)	SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE KIDNEY, URETER, AND BLADDER: RENAL FUNCTION TESTS DEPRESSED	Medical Journal of Australia. Vol. 141, Pg. 528, 1984.
women	TDLo	oral	80mg/kg (80mg/kg)	SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE SENSE ORGANS AND SPECIAL SENSES: CHANGE IN ACUITY: EAR GASTROINTESTINAL: NAUSEA OR VOMITING	British Medical Journal. Vol. 287, Pg. 1700, 1983.
women	TDLo	oral	110mg/kg (110mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE SENSE ORGANS AND SPECIAL SENSES: CHANGE IN ACUITY: EAR SENSE ORGANS AND SPECIAL SENSES: TINNITUS: EAR	American Journal of Emergency Medicine. Vol. 16, Pg. 214, 1998.
women	TDLo	oral	130mg/kg (130mg/kg)	SENSE ORGANS AND SPECIAL SENSES: CHANGE IN ACUITY: EAR BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	American Journal of Emergency Medicine. Vol. 9, Pg. 318,

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Quinine sulphate cas no:804-63-7

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