4-Thiazolidinecarboxylicacid, 2-(2-hydroxyphenyl)-3-(3-mercapto-1-oxopropyl)-, (2R,4R)- cas no:80830-42-8

Name4-Thiazolidinecarboxylicacid, 2-(2-hydroxyphenyl)-3-(3-mercapto-1-oxopropyl)-, (2R,4R)-
CAS80830-42-8
Synonyms4-Thiazolidinecarboxylicacid, 2-(2-hydroxyphenyl)-3-(3-mercapto-1-oxopropyl)-, (2R-cis)-; Fentiapril;Rentiapril; SA 446
Molecular FormulaC13H15 N O4 S2
Molecular Weight313.41

refractive index1.66

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	200mg/kg (200mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Oyo Yakuri. Pharmacometrics. Vol. 31, Pg. 235, 1986.
mouse	LD50	intraperitoneal	1gm/kg (1000mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Oyo Yakuri. Pharmacometrics. Vol. 31, Pg. 235, 1986.
mouse	LD50	intravenous	946mg/kg (946mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: ATAXIA	Oyo Yakuri. Pharmacometrics. Vol. 31, Pg. 235, 1986.
mouse	LD50	oral	8050mg/kg (8050mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Oyo Yakuri. Pharmacometrics. Vol. 31, Pg. 235, 1986.
mouse	LD50	subcutaneous	2213mg/kg (2213mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: CYANOSIS BEHAVIORAL: ATAXIA	Oyo Yakuri. Pharmacometrics. Vol. 31, Pg. 235, 1986.
rat	LD50	intraperitoneal	921mg/kg (921mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Oyo Yakuri. Pharmacometrics. Vol. 31, Pg. 235, 1986.
rat	LD50	intravenous	884mg/kg (884mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Oyo Yakuri. Pharmacometrics. Vol. 31, Pg. 235, 1986.
rat	LD50	oral	8290mg/kg (8290mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Oyo Yakuri. Pharmacometrics. Vol. 31, Pg. 235, 1986.
rat	LD50	subcutaneous	1369mg/kg (1369mg/kg)	BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Oyo Yakuri. Pharmacometrics. Vol. 31, Pg. 235, 1986.