Dehydrocholic acid cas no:81-23-2
Synonyms: 5b-Cholan-24-oic acid,3,7,12-trioxo- (8CI);3,7,12-Tri-keto-5b-Cholan-24-oic acid;3,7,12-Triketo-5b-cholanic acid;3,7,12-Triketocholanic acid;3,7,12-Trioxo-5b-cholan-24-oic acid;3,7,12-Trioxo-5b-cholanic acid;3,7,12-Trioxocholanic acid;Acolen;Bilidren;Bilostat;Cholagon;Cholan DH;Cholepatin;Cholic acid, dehydro-;Cholimed;Chologon;DHC;Decholin;Dehychol;Dehycon;
NameDehydrocholic acid
CAS81-23-2
Synonyms5b-Cholan-24-oic acid,3,7,12-trioxo- (8CI);3,7,12-Tri-keto-5b-Cholan-24-oic acid;3,7,12-Triketo-5b-cholanic acid;3,7,12-Triketocholanic acid;3,7,12-Trioxo-5b-cholan-24-oic acid;3,7,12-Trioxo-5b-cholanic acid;3,7,12-Trioxocholanic acid;Acolen;Bilidren;Bilostat;Cholagon;Cholan DH;Cholepatin;Cholic acid, dehydro-;Cholimed;Chologon;DHC;Decholin;Dehychol;Dehycon;
EINECS(EC#)201-335-7
Molecular FormulaC24H34O5
Molecular Weight402.53
Appearancewhite to off-white amorphous powder
alpha29 º (C=2, DIOXANE)
refractive index30.5 ° (C=2, Dioxane)
storage tempStore in a tightly closed container. Store in a cool, dry area away from incompatible substances.
Safety
Safety Statements: 24/25
S24/25:Avoid contact with skin and eyes.
WGK Germany: 2
RTECS: FZ2300000
Moderately toxic by ingestion, intravenous, intramuscular, and subcutaneous routes. When heated to decomposition it emits acrid smoke and fumes.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intravenous |
1492mg/kg (1492mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS |
Japanese Journal of Pharmacology. Vol. 22, Pg. 235, 1972.
|
| mouse |
LD50 |
oral |
3100mg/kg (3100mg/kg) |
|
Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 857, 1962. |
| mouse |
LD50 |
subcutaneous |
1620mg/kg (1620mg/kg) |
|
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 116, Pg. 154, 1958.
|
| rat |
LD50 |
intramuscular |
1500mg/kg (1500mg/kg) |
|
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 222, Pg. 244, 1954.
|
| rat |
LD50 |
intravenous |
750mg/kg (750mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 495, 1982. |
| rat |
LD50 |
oral |
4gm/kg (4000mg/kg) |
|
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 116, Pg. 154, 1958.
|
