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5H-Furo[3,2-g][1]benzopyran-5-one,4,9-dimethoxy-7-methyl- cas no:82-02-0

Synonyms: 4,9-Dimethoxy-7-methyl-5-oxo-1,8-dioxabenz[f]indene;4,9-Dimethoxy-7-methyl-5-oxofuro[3,2-g]-1,2-chromene;4,9-Dimethoxy-7-methyl-5-oxofuro[3,2-g][1]benzopyran;4,9-Dimethoxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-one;5,8-Dimethoxy-2-methyl-4',5'-furano-6,7-chromone;5,8-Dimethoxy-2-methyl-4',5'-furo-6,7-chromone;5,8-Dimethoxy-2-methyl-6,7-furanochromone; Amicardien; Amicardine; Amikellin;Ammipuran; Ammispasmin; Ammivin; Ammivisnagen; Benecardin; Benekardin;Cardio-khellin; Corafurone; Coronin; Eskel; Gynokhellan; Gynokhellin; Hkelfren;Kalangin; Kelamin; Kelicor; Kelicorin; Kellosal; Keloid; Khelfren; Khelisem;Khellin; Khelline I; Khelloyd; Lynamine; Medekellin; Methafrone; NSC 25509; NSC37744; NSC 8519; Norkel; Simeskellina; Vasokellina; Visammin; Viscardan;Visnagalin; Visnagen

Identification
Name5H-Furo[3,2-g][1]benzopyran-5-one,4,9-dimethoxy-7-methyl-
CAS82-02-0
Synonyms4,9-Dimethoxy-7-methyl-5-oxo-1,8-dioxabenz[f]indene;4,9-Dimethoxy-7-methyl-5-oxofuro[3,2-g]-1,2-chromene;4,9-Dimethoxy-7-methyl-5-oxofuro[3,2-g][1]benzopyran;4,9-Dimethoxy-7-methyl-5H-furo[3,2-g][1]benzopyran-5-one;5,8-Dimethoxy-2-methyl-4',5'-furano-6,7-chromone;5,8-Dimethoxy-2-methyl-4',5'-furo-6,7-chromone;5,8-Dimethoxy-2-methyl-6,7-furanochromone; Amicardien; Amicardine; Amikellin;Ammipuran; Ammispasmin; Ammivin; Ammivisnagen; Benecardin; Benekardin;Cardio-khellin; Corafurone; Coronin; Eskel; Gynokhellan; Gynokhellin; Hkelfren;Kalangin; Kelamin; Kelicor; Kelicorin; Kellosal; Keloid; Khelfren; Khelisem;Khellin; Khelline I; Khelloyd; Lynamine; Medekellin; Methafrone; NSC 25509; NSC37744; NSC 8519; Norkel; Simeskellina; Vasokellina; Visammin; Viscardan;Visnagalin; Visnagen
EINECS(EC#)201-392-8
Molecular FormulaC14H12 O5
Molecular Weight260.2421
Chemical Properties
Appearancelight yellow crystalline
refractive index1.595
storage temp−20°C
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard T: Toxic;
Risk R25
Safety

Poison by ingestion, intraperitoneal, intramuscular, and intravenous routes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes. A vasodilator.
 

Hazard Codes: T
Risk Statements:
23:  Toxic by inhalation
24:  Toxic in contact with skin 
25:  Toxic if swallowed
36:  Irritating to the eyes
37:  Irritating to the respiratory system
38:  Irritating to the skin
Safety Statements:
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:  Wear suitable protective clothing 
37:  Wear suitable gloves
39:  Wear eye/face protection
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)


Toxicity
1.    

orl-rat LD50:68,800 µg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 11 (1961),915.
2.    

ipr-rat LD50:70 mg/kg

    JDGRAX    Journal of Drug Research. 9 (1-2),(1977),35.
3.    

ivn-rat LD50:34 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 11 (1961),848.
4.    

orl-mus LD50:50,800 µg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 11 (1961),915.
5.    

ipr-mus LD50:155 mg/kg

    FRPSAX    Farmaco, Edizione Scientifica. 13 (1958),561.
6.    

ivn-mus LD50:30,600 µg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 11 (1961),915.
7.    

ims-mus LD50:83 mg/kg

    JDGRAX    Journal of Drug Research. 9 (1-2),(1977),35.

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