82159-09-9|EpalrestatProducts Supply - Chemical intermediates Network

Epalrestat cas no:82159-09-9

Synonyms: 2-[(5Z)-5-[(E)-2-methyl-3-phenyl-prop-2-enylidene]-4-oxo-2-sulfanylidene-thiazolidin-3-yl]acetic acid;3-Thiazolidineacetic acid,5-[(2E)-2-methyl-3-phenyl-2-propenylidene]- 4-oxo-2-thioxo-,(5Z)-;3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (E,E)-;Kinedak;Epalrestat (JAN);5-((Z,E)-beta-Methylcinnamylidene)-4-oxo-2-thioxo-3-thiazolidineacetic acid;Epalrestat [INN];Kinedak (TN);Ono 2235;Epalrestatum [Latin];Properties: orange red crystalline powder, with special odor;Epalrestate;Epatrestat;

Identification

NameEpalrestat
CAS82159-09-9
Synonyms2-[(5Z)-5-[(E)-2-methyl-3-phenyl-prop-2-enylidene]-4-oxo-2-sulfanylidene-thiazolidin-3-yl]acetic acid;3-Thiazolidineacetic acid,5-[(2E)-2-methyl-3-phenyl-2-propenylidene]- 4-oxo-2-thioxo-,(5Z)-;3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (E,E)-;Kinedak;Epalrestat (JAN);5-((Z,E)-beta-Methylcinnamylidene)-4-oxo-2-thioxo-3-thiazolidineacetic acid;Epalrestat [INN];Kinedak (TN);Ono 2235;Epalrestatum [Latin];Properties: orange red crystalline powder, with special odor;Epalrestate;Epatrestat;
Molecular FormulaC₁₅H₁₃NO₃S₂
Molecular Weight319.39862

Chemical Properties

AppearanceDeep red acicular crystal
refractive index1.705
storage tempStore in original container in a cool dark place.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 1gm/kg (1000mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
mouse	LD50	intraperitoneal	687mg/kg (687mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
mouse	LD50	intravenous	255ug/kg (0.255mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
mouse	LD50	oral	3200mg/kg (3200mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
mouse	LD50	subcutaneous	> 3gm/kg (3000mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
rat	LD50	intraperitoneal	922gm/kg (922000mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
rat	LD50	intravenous	255ug/kg (0.255mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
rat	LD50	oral	5300ug/kg (5.3mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
rat	LD50	subcutaneous	> 3gm/kg (3000mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.

supplier list

Changzhou Leo Chemical Co.,Ltd.: Tel:; Address: NO. 538 XINQING ROAD, XINZHA TOWN, ZHONGLOU DISTRICT, CHANGZHOU, JIANGSU, CHINA

APAC Pharmaceutical, LLC: Tel:+1-(410)-997-5552, 469-0727; Address: 6851 Oak Hall Lane, Suite 101, Columbia, Maryland 21045,

Shanghai Jinhuan Chemical Co., Ltd.: Tel:+86-(21)-61420008, 67285091; Address: Room 1601, No. 198 North Zhongshan Road, Zhabei District, Shanghai 200071,

Watson International Ltd.: Tel:+86-(512)-55117610; Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332,

Hangzhou Hetd Industry Co.,Ltd: Tel:+86-571-81958080; Address: No.8,Xiyuan Yiroad,Xihu Industrial Park,hangzhou

Shanghai Jinhuan Chemical CO.,LTD.: Tel:86-21-61420008; Address: NO.198, ZHONGSHAN ROAD, SHANGHAI, CHINA

Zhejiang East-Asia Pharmaceutical Co., Ltd.: Tel:+86-576-84285079; Address: Xuanzhu Fanglu, Haiyou Town, Sanmen County, Taizhou City, Zhejiang, China.

Taizhou Hengfeng Pharmaceutical & Chemical Co., Ltd.: Tel:0086-576-85993534 85993403; Address: Shuiyang chemical development zone, linhai, china

Hangzhou J&H Chemical Co., Ltd: Tel:86-571-87396430; Address: No.200 Zhenhua Rd.Xihu Industrial Park, Hangzhou 310030, China

Nanjing Bangnuo Biotechnology Co., Ltd: Tel:86-1732-7098554; Address: shuanglong road,jiangning, nanjing,jiangsu

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

Hubei XinRunde Chemical Co., Ltd: Tel:86-27-83214668; Address: East and West Lake District, Wuhan, China

Epalrestat cas no:82159-09-9

Directory

supplier list