82159-09-9|EpalrestatProducts Supply - Chemical intermediates Network

Epalrestat cas no:82159-09-9

Synonyms: 2-[(5Z)-5-[(E)-2-methyl-3-phenyl-prop-2-enylidene]-4-oxo-2-sulfanylidene-thiazolidin-3-yl]acetic acid;3-Thiazolidineacetic acid,5-[(2E)-2-methyl-3-phenyl-2-propenylidene]- 4-oxo-2-thioxo-,(5Z)-;3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (E,E)-;Kinedak;Epalrestat (JAN);5-((Z,E)-beta-Methylcinnamylidene)-4-oxo-2-thioxo-3-thiazolidineacetic acid;Epalrestat [INN];Kinedak (TN);Ono 2235;Epalrestatum [Latin];Properties: orange red crystalline powder, with special odor;Epalrestate;Epatrestat;

Identification

NameEpalrestat
CAS82159-09-9
Synonyms2-[(5Z)-5-[(E)-2-methyl-3-phenyl-prop-2-enylidene]-4-oxo-2-sulfanylidene-thiazolidin-3-yl]acetic acid;3-Thiazolidineacetic acid,5-[(2E)-2-methyl-3-phenyl-2-propenylidene]- 4-oxo-2-thioxo-,(5Z)-;3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (E,E)-;Kinedak;Epalrestat (JAN);5-((Z,E)-beta-Methylcinnamylidene)-4-oxo-2-thioxo-3-thiazolidineacetic acid;Epalrestat [INN];Kinedak (TN);Ono 2235;Epalrestatum [Latin];Properties: orange red crystalline powder, with special odor;Epalrestate;Epatrestat;
Molecular FormulaC₁₅H₁₃NO₃S₂
Molecular Weight319.39862

Chemical Properties

AppearanceDeep red acicular crystal
refractive index1.705
storage tempStore in original container in a cool dark place.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 1gm/kg (1000mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
mouse	LD50	intraperitoneal	687mg/kg (687mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
mouse	LD50	intravenous	255ug/kg (0.255mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
mouse	LD50	oral	3200mg/kg (3200mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
mouse	LD50	subcutaneous	> 3gm/kg (3000mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
rat	LD50	intraperitoneal	922gm/kg (922000mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
rat	LD50	intravenous	255ug/kg (0.255mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
rat	LD50	oral	5300ug/kg (5.3mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
rat	LD50	subcutaneous	> 3gm/kg (3000mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.

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Saniver Limited: Tel:; Address: 805 Harbour Centre, Tower 2, 8 Hok Cheung St., Hunghom, Kowloon, Hong Kong.

Luna Chemicals Co.,Ltd.: Tel:; Address: 1502-1503,No.310 North Zhong Shan Rd., Hangzhou,China

Ancheng Pharma Limited: Tel:+86-755-82713308; Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China

Hangzhou Cowin Pharma Co., Ltd.: Tel:; Address: B-12F,International Garden,No.158 Tianmushan Road,Hangzhou,China

Changzhou Leo Chemical Co.,Ltd.: Tel:; Address: NO. 538 XINQING ROAD, XINZHA TOWN, ZHONGLOU DISTRICT, CHANGZHOU, JIANGSU, CHINA

Borun Chemical Co.,Ltd.: Tel:+86-574- 87178138;87297407; Address: Unit 809, Liuting Xingzuo, Cangsong Road, Ningbo, China

Taizhou Xingcheng Chemphar Co., Ltd.: Tel:86-576-88551200; Address: B Area. 10 Floor.Yaodadasha. 289#.Shifu Road.Taizhou.Zhejiang.China

Taizhou Hengfeng Pharmaceutical&chemical Co., Ltd...: Tel:; Address: Shuiyang chemical development zone, linhai, china

Hangzhou Verychem Science And Technology Co. Ltd.: Tel:; Address: 1108A, 316 Jiaogong Road, Hangzhou, Zhejiang, China

HANGZHOU THINK CHEMICAL CO., LTD.: Tel:; Address: ROOM 719 BUILDING D MEIDU PLAZA 789 MOGANSHAN ROAD HANGZHOU CHINA

KOA SHOJI CO., LTD.: Tel:+81-45-540-6985; Address: 17-5, Minowa-cho, 2-chome, Kohoku-ku, Yokohama-shi, Kanagawa, 223-0051, Japan

Sanyo Chemical Laboratroy Co., Ltd.: Tel:+81 72-361-6633/6634; Address: 148-1, Tajii, Mihara-ku, Sakai city Osaka Pref., 587-0012, Japan

Shanghai Entropy Chemical Co., Ltd.: Tel:+86-(21)-5512-2488; Address: Fengxian District, Shanghai 201400,

Qilong Chemical Co., Ltd.: Tel:86-574-63858500; Address: No.586, Jiangnan Road,High-tech Park, Ningbo, Zhejiang 315040,

Inter-Chemical Ltd.: Tel:+86-(755)-82187211, 82192202; Address: B-1108/1109, Tian An International Bldg., RenMin Nan Road, ShenZhen 518005,

Epalrestat cas no:82159-09-9

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