82159-09-9|EpalrestatProducts Supply - Chemical intermediates Network

Epalrestat cas no:82159-09-9

Synonyms: 2-[(5Z)-5-[(E)-2-methyl-3-phenyl-prop-2-enylidene]-4-oxo-2-sulfanylidene-thiazolidin-3-yl]acetic acid;3-Thiazolidineacetic acid,5-[(2E)-2-methyl-3-phenyl-2-propenylidene]- 4-oxo-2-thioxo-,(5Z)-;3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (E,E)-;Kinedak;Epalrestat (JAN);5-((Z,E)-beta-Methylcinnamylidene)-4-oxo-2-thioxo-3-thiazolidineacetic acid;Epalrestat [INN];Kinedak (TN);Ono 2235;Epalrestatum [Latin];Properties: orange red crystalline powder, with special odor;Epalrestate;Epatrestat;

Identification

NameEpalrestat
CAS82159-09-9
Synonyms2-[(5Z)-5-[(E)-2-methyl-3-phenyl-prop-2-enylidene]-4-oxo-2-sulfanylidene-thiazolidin-3-yl]acetic acid;3-Thiazolidineacetic acid,5-[(2E)-2-methyl-3-phenyl-2-propenylidene]- 4-oxo-2-thioxo-,(5Z)-;3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propenylidene)-4-oxo-2-thioxo-, (E,E)-;Kinedak;Epalrestat (JAN);5-((Z,E)-beta-Methylcinnamylidene)-4-oxo-2-thioxo-3-thiazolidineacetic acid;Epalrestat [INN];Kinedak (TN);Ono 2235;Epalrestatum [Latin];Properties: orange red crystalline powder, with special odor;Epalrestate;Epatrestat;
Molecular FormulaC₁₅H₁₃NO₃S₂
Molecular Weight319.39862

Chemical Properties

AppearanceDeep red acicular crystal
refractive index1.705
storage tempStore in original container in a cool dark place.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	> 1gm/kg (1000mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
mouse	LD50	intraperitoneal	687mg/kg (687mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
mouse	LD50	intravenous	255ug/kg (0.255mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
mouse	LD50	oral	3200mg/kg (3200mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
mouse	LD50	subcutaneous	> 3gm/kg (3000mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
rat	LD50	intraperitoneal	922gm/kg (922000mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
rat	LD50	intravenous	255ug/kg (0.255mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
rat	LD50	oral	5300ug/kg (5.3mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.
rat	LD50	subcutaneous	> 3gm/kg (3000mg/kg)	?	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 23, Pg. 201, 1992.

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Luna Chemicals Co.,Ltd.: Tel:; Address: 1502-1503,No.310 North Zhong Shan Rd., Hangzhou,China

IFFECT CHEMPHAR CO., LTD.: Tel:86-25-84679300; Address: 509, FuXin International Building, No.359 HongWu R

Ancheng Pharma Limited: Tel:+86-755-82713308; Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China

Hangzhou Cowin Pharma Co., Ltd.: Tel:; Address: B-12F,International Garden,No.158 Tianmushan Road,Hangzhou,China

Chemfar Ltd.: Tel:; Address: 16E,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China

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Cangzhou Senary Chemical Science-tech Co.,Ltd.: Tel:; Address: 168 Jinde Road, Changzhou, Hebei, China

Wudi Reaction Pharma&Chemical Co.,Ltd.: Tel:; Address: Xinhai Industrial Park, Wudi County, Shandong Province, China

Borun Chemical Co.,Ltd.: Tel:+86-574- 87178138;87297407; Address: Unit 809, Liuting Xingzuo, Cangsong Road, Ningbo, China

Hangzhou Hysen Pharma Co., Ltd: Tel:; Address: No.808, B Building,Zijin Plaza, No.701,Gudun ROAD,Hangzhou

Taizhou Xingcheng Chemphar Co., Ltd.: Tel:86-576-88551200; Address: B Area. 10 Floor.Yaodadasha. 289#.Shifu Road.Taizhou.Zhejiang.China

Taizhou Taifeng Chemical Co., Ltd.: Tel:; Address: Jiaojiang District, Taizhou City, Zhejiang Province, China

Hangzhou Verychem Science And Technology Co. Ltd.: Tel:; Address: 1108A, 316 Jiaogong Road, Hangzhou, Zhejiang, China

HANGZHOU THINK CHEMICAL CO., LTD.: Tel:; Address: ROOM 719 BUILDING D MEIDU PLAZA 789 MOGANSHAN ROAD HANGZHOU CHINA

Sanyo Chemical Laboratroy Co., Ltd.: Tel:+81 72-361-6633/6634; Address: 148-1, Tajii, Mihara-ku, Sakai city Osaka Pref., 587-0012, Japan

Epalrestat cas no:82159-09-9

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