2,6,7-Trioxa-1-phosphabicyclo[2.2.2]octane,4-ethyl- cas no:824-11-3

Name2,6,7-Trioxa-1-phosphabicyclo[2.2.2]octane,4-ethyl-
CAS824-11-3
Synonyms1,3-Propanediol,2-ethyl-2-(hydroxymethyl)-, cyclic phosphite (1:1) (8CI); 1,3-Propanediol,2-ethyl-2-(hydroxymethyl)-, cyclic phosphite (7CI);1-Ethyl-3,5,8-trioxa-4-phospha[2.2.2]bicyclooctane;2-Ethyl-2-hydroxymethyl-1,3-propanediol cyclic phosphite;4-Ethyl-1-phospha-2,6,7-trioxabicyclo[2.2.2]octane;4-Ethyl-2,6,7-trioxa-1-phosphabicyclo[2.2.2]octane; ETPB; Ethriol phosphite;NSC 127561; Trimethylolpropane cyclic phosphite (1:1); Trimethylolpropanephosphite
EINECS(EC#)212-523-3
Molecular FormulaC6H11 O3 P
Molecular Weight162.14

Hazardclass6.1(a)

Hazard T+: Very toxic;
Risk 21-28
Safety

Poison by ingestion, inhalation, skin contact, intraperitoneal, and intravenous routes. When heated to decomposition it emits toxic fumes of PO_x.Safety information of Trimethylolpropane phosphite (CAS NO.824-11-3):
Hazard Codes  T+
Risk Statements 
21 Harmful in contact with skin
28 Very Toxic if swallowed
Safety Statements 
28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
36/37 Wear suitable protective clothing and gloves
45 In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR  UN 3464 6.1/PG 2
WGK Germany  3
RTECS  TY6650000
F  10-18
HazardClass  6.1(a)
PackingGroup  I

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LD50	oral	2500ug/kg (2.5mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Archives of Toxicology. Vol. 35, Pg. 149, 1976.
chicken	LD50	oral	75mg/kg (75mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Archives of Toxicology. Vol. 35, Pg. 149, 1976.
dog	LD50	oral	5mg/kg (5mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Archives of Toxicology. Vol. 35, Pg. 149, 1976.
guinea pig	LD50	oral	20mg/kg (20mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Archives of Toxicology. Vol. 35, Pg. 149, 1976.
hamster	LD50	oral	8mg/kg (8mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Archives of Toxicology. Vol. 35, Pg. 149, 1976.
mouse	LD50	intraperitoneal	1100ug/kg (1.1mg/kg)		Chemical & Engineering News. Vol. 52(1), Pg. 56, 1974.
mouse	LD50	oral	3320ug/kg (3.32mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Archives of Toxicology. Vol. 35, Pg. 149, 1976.
mouse	LD50	skin	4mg/kg (4mg/kg)		Science. Vol. 182, Pg. 1135, 1973.
mouse	LDLo	intravenous	1mg/kg (1mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS	European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 13, Pg. 207, 1978.
quail	LD50	oral	10mg/kg (10mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Archives of Toxicology. Vol. 35, Pg. 149, 1976.
rabbit	LD50	oral	50mg/kg (50mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Archives of Toxicology. Vol. 35, Pg. 149, 1976.
rat	LCLo	inhalation	10ppm/4H (10ppm)	BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	British Journal of Industrial Medicine. Vol. 27, Pg. 1, 1970.
rat	LD50	intraperitoneal	1020ug/kg (1.02mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Archives of Toxicology. Vol. 35, Pg. 149, 1976.
rat	LD50	oral	8390ug/kg (8.39mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD	Archives of Toxicology. Vol. 35, Pg. 149, 1976.
rat	LD50	skin	929mg/kg (929mg/kg)		Archives of Toxicology. Vol. 35, Pg. 149, 1976.