5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-,(2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)- cas no:82547-81-7
Synonyms: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-,(2,2-dimethyl-1-oxopropoxy)methyl ester, [6R-[6a,7b(Z)]]-; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-,(2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)- (9CI); Antibiotic T 2588;Cefteram pivoxil; Ro 19-5248; T 2588; Tomiron; Tomiron 100
Name5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-,(2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)-
CAS82547-81-7
Synonyms5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-,(2,2-dimethyl-1-oxopropoxy)methyl ester, [6R-[6a,7b(Z)]]-; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(5-methyl-2H-tetrazol-2-yl)methyl]-8-oxo-,(2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)- (9CI); Antibiotic T 2588;Cefteram pivoxil; Ro 19-5248; T 2588; Tomiron; Tomiron 100
Molecular FormulaC22H27 N9 O7 S2
Molecular Weight593.70
refractive index1.744
storage tempHygroscopic, -20°C Freezer, Under Inert Atmosphere
Safety
Mildly toxic by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| dog |
LD50 |
oral |
> 2gm/kg (2000mg/kg) |
|
Chemotherapy Vol. 34(Suppl, |
| mouse |
LD50 |
intraperitoneal |
5860mg/kg (5860mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Chemotherapy Vol. 34(Suppl, |
| mouse |
LD50 |
oral |
> 6gm/kg (6000mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Chemotherapy Vol. 34(Suppl, |
| mouse |
LD50 |
subcutaneous |
> 6gm/kg (6000mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Chemotherapy Vol. 34(Suppl, |
| rat |
LD50 |
intraperitoneal |
5090mg/kg (5090mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Chemotherapy Vol. 34(Suppl, |
| rat |
LD50 |
oral |
> 6gm/kg (6000mg/kg) |
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Chemotherapy Vol. 34(Suppl, |
| rat |
LD50 |
subcutaneous |
> 6gm/kg (6000mg/kg) |
SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" |
Chemotherapy Vol. 34(Suppl, |
