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Home > products > 3-Isoquinolinecarboxylicacid,2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-,hydrochloride (1:1), (3S)-

3-Isoquinolinecarboxylicacid,2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-,hydrochloride (1:1), (3S)- cas no:82586-52-5

Synonyms: (3S)-2-((2S)-N-((1S)-1-Carboxy-3-phenylpropyl)alanyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid, 2-ethyl ester, monohydrochloride;Moexipril HCl;UNII-Q1UMG3UH45;RS 10085-197;SPM 925;Univasc;CI 925;

Identification
Name3-Isoquinolinecarboxylicacid,2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-,hydrochloride (1:1), (3S)-
CAS82586-52-5
Synonyms(3S)-2-((2S)-N-((1S)-1-Carboxy-3-phenylpropyl)alanyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid, 2-ethyl ester, monohydrochloride;Moexipril HCl;UNII-Q1UMG3UH45;RS 10085-197;SPM 925;Univasc;CI 925;
Molecular FormulaC27H34N2O7.ClH
Molecular Weight535.029
Chemical Properties
Appearancea fine white to off-white powder
storage temp2-8°C
Safety Data

Hazard N:Dangerous for the environment
Risk R50
Safety

Moderately toxic by ingestion and intravenous routes. When heated to decomposition it emits toxic vapors of NOx, HCl, and Cl?.
Hazard Codes:
DangerousN
Risk Statements:
R50:Very toxic to aquatic organisms.
Safety Statements:
S60:This material and its container must be disposed of as hazardous waste.?
RIDADR: UN 3077 9/PG 3
RTECS: NW7174500


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral > 900mg/kg (900mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 47, Pg. 132, 1997.
mouse LD50 intravenous 830mg/kg (830mg/kg) behavioral: changes in motor activity (specific assay) behavioral: ataxia lungs, thorax, or respiration: dyspnea Arzneimittel-Forschung. Drug Research. Vol. 47, Pg. 132, 1997.
mouse LD50 oral 2209mg/kg (2209mg/kg) behavioral: somnolence (general depressed activity) Arzneimittel-Forschung. Drug Research. Vol. 47, Pg. 132, 1997.
rat LD50 intravenous 461mg/kg (461mg/kg) behavioral: changes in motor activity (specific assay) behavioral: ataxia lungs, thorax, or respiration: dyspnea Arzneimittel-Forschung. Drug Research. Vol. 47, Pg. 132, 1997.
rat LD50 oral 4015mg/kg (4015mg/kg) behavioral: somnolence (general depressed activity) gastrointestinal: "hypermotility, diarrhea" skin and appendages (skin): hair: other Arzneimittel-Forschung. Drug Research. Vol. 47, Pg. 132, 1997.

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Hangzhou Sida Organic Chemical Co., Ltd.
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Beijing JHYB Pharmaceutical Technology Co., Ltd
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Wuhan Sunrise TEnology development company limited
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AOPHARM
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Hubei XinRunde Chemical Co., Ltd
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Wuhan Dahua Weiye Pharmaceutical Co.,Ltd
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Address: daijiashan 45,jiangan economic departmen zone,wuhan,hubei,China
Wuhan Senwayer Century chemical Co.,Ltd
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Hangzhou Dayangchem Co., Ltd.
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Finetech Industry limited.
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Wuhan Fortuna Chemical Co., Ltd.
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HEBEI CUI FENG IMPORT&EXPORT TRADE CO.,LTD
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run-biotech Co., Ltd.
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Boc Sciences
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Address: 45-16 Ramsey Road Shirley, NY 11967, USA
Amadis Chemical Co.,Ltd.
Tel:86-571-89925085
Address: SaiBo Pioneer Park.No.168,Jianding Road,Jianggan District.

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