82956-11-4|Nafamostat mesylateProducts Supply - Chemical intermediates Network

Nafamostat mesylate cas no:82956-11-4

Synonyms: Benzoic acid, 4-((aminoiminomethyl)amino)-, 6-(aminoiminomethyl)-2-naphthalenyl ester, dimethanesulfonate;Ronastat;Nafamostat mesylate (USAN);Nafamostat dimethanesulfonate;Nafamostat mesilate;Benzoic acid,4-[(aminoiminomethyl)amino]-,6- (aminoiminomethyl)-2-naphthalenyl ester,dimethanesulfonate;FUT 175;Futhan;[N-[4-[6-(azaniumylcarbonimidoyl)naphthalen-2-yl]oxycarbonylphenyl]carbamimidoyl]azanium; methanesulfonate;Nafamostat mesilate (JAN);Nafamostat mesylate [USAN];Ronastat (TN);Nafamostat Mesilate(CAS No: 82956-11-4);6-Amidino-2-naphthyl 4-guanidinobenzoate dimethanesulfonate;

Identification

NameNafamostat mesylate
CAS82956-11-4
SynonymsBenzoic acid, 4-((aminoiminomethyl)amino)-, 6-(aminoiminomethyl)-2-naphthalenyl ester, dimethanesulfonate;Ronastat;Nafamostat mesylate (USAN);Nafamostat dimethanesulfonate;Nafamostat mesilate;Benzoic acid,4-[(aminoiminomethyl)amino]-,6- (aminoiminomethyl)-2-naphthalenyl ester,dimethanesulfonate;FUT 175;Futhan;[N-[4-[6-(azaniumylcarbonimidoyl)naphthalen-2-yl]oxycarbonylphenyl]carbamimidoyl]azanium; methanesulfonate;Nafamostat mesilate (JAN);Nafamostat mesylate [USAN];Ronastat (TN);Nafamostat Mesilate(CAS No: 82956-11-4);6-Amidino-2-naphthyl 4-guanidinobenzoate dimethanesulfonate;
Molecular FormulaC₂₁H₂₅N₅O₈S₂
Molecular Weight539.63

Chemical Properties

AppearanceTan to pale orange solid
storage tempRoom temp

Safety Data

Safety

RTECS of 6-Amidino-2-naphthyl 4-guanidinobenzoate dimethanesulfonate (CAS NO.82956-11-4): DG2736000
A poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic vapors of NO_x and SO_x.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mammal (species unspecified)	LD50	intraperitoneal	200mg/kg (200mg/kg)	United States Patent Document. Vol. #4454338,
mammal (species unspecified)	LD50	oral	2500mg/kg (2500mg/kg)	United States Patent Document. Vol. #4454338,
mouse	LD50	intraperitoneal	269mg/kg (269mg/kg)	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.
mouse	LD50	intravenous	24400ug/kg (24.4mg/kg)	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.
mouse	LD50	oral	4600mg/kg (4600mg/kg)	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.
mouse	LD50	subcutaneous	6180mg/kg (6180mg/kg)	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.
rat	LD50	intraperitoneal	162mg/kg (162mg/kg)	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.
rat	LD50	intravenous	16400ug/kg (16.4mg/kg)	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.
rat	LD50	oral	3050mg/kg (3050mg/kg)	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.
rat	LD50	subcutaneous	9200mg/kg (9200mg/kg)	Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986.

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Nafamostat mesylate cas no:82956-11-4

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