DDA cas no:83-05-6

NameDDA
CAS83-05-6
SynonymsAceticacid, bis(p-chlorophenyl)- (6CI,7CI,8CI);2,2-Bis(4-chlorophenyl)acetic acid;Bis(4-chlorophenyl)acetic acid;Bis(p-chlorophenyl)acetic acid;Benzeneacetic acid,4-chloro-a-(4-chlorophenyl)-;DDA(degradation product);Di(p-chlorophenyl)acetic acid;Dichlorodiphenylaceticacid;NSC 4279;p,p'-DDA;
EINECS(EC#)201-451-8
Molecular FormulaC₁₄H₁₀Cl₂O₂
Molecular Weight281.14

refractive index1.616
storage temp0-6°C

HazardclassIRRITANT

Hazard Xn: Harmful;
Risk R20/21/22
Safety Moderately toxic by ingestion. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl−.

CHEMICAL IDENTIFICATION

RTECS NUMBER :

AF5475000

CHEMICAL NAME :

Acetic acid, bis(p-chlorophenyl)-

CAS REGISTRY NUMBER :

83-05-6

BEILSTEIN REFERENCE NO. :

1913593

LAST UPDATED :

199706

DATA ITEMS CITED :

8

MOLECULAR FORMULA :

C14-H10-Cl2-O2

MOLECULAR WEIGHT :

281.14

WISWESSER LINE NOTATION :

QYVR DG&R DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

740 mg/kg

TOXIC EFFECTS :

Gastrointestinal - hypermotility, diarrhea Gastrointestinal - nausea or vomiting Liver - other changes

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

590 mg/kg

TOXIC EFFECTS :

Behavioral - hallucinations, distorted perceptions

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

250 mg/kg

SEX/DURATION :

female 15-19 day(s) after conception

TOXIC EFFECTS :

Reproductive - Specific Developmental Abnormalities - urogenital system

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Intraperitoneal

DOSE :

350 mg/kg

SEX/DURATION :

female 7 day(s) pre-mating

TOXIC EFFECTS :

Reproductive - Maternal Effects - uterus, cervix, vagina

TYPE OF TEST :

Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :

Cytogenetic analysis

TEST SYSTEM :

Rodent - rat Cells - not otherwise specified

DOSE/DURATION :

150 mg/L/24H (Continuous)

REFERENCE :

TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 22,355,1972