1,4-Pentanediamine,N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl- cas no:83-89-6

Name1,4-Pentanediamine,N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-
CAS83-89-6
SynonymsAcridine,6-chloro-9-[[4-(diethylamino)-1-methylbutyl]amino]-2-methoxy- (8CI); (?à)-Quinacrine;6-Chloro-9-[[4-(diethylamino)-1-methylbutyl]amino]-2-methoxyacridine; Acrichin;Acrinamine; Acriquine; Akrichin; Antimalarina; Atabrine; Haffkinine; Italchine;Mepacrine; Quinacrine; ST 439
EINECS(EC#)201-508-7
Molecular FormulaC23H30 Cl N3 O
Molecular Weight399.9625

Hazard Xn: Harmful;
Risk R36/37/38
Safety

Poison by intravenous and subcutaneous routes. Moderately toxic by ingestion. Mutation data reported. Experimental reproductive effects. Has been implicated in aplastic anemia. When heated to decomposition, it emits very toxic fumes of Cl⁻ and NO_x.
Hazard CodesXn
Risk Statements 36/37/38-22 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R22:Harmful if swallowed.
Safety Statements 37/39-26
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39:Wear suitable gloves and eye/face protection.

1.		mma-sat 500 µg/plate		TXAPA9    Toxicology and Applied Pharmacology. 52 (1980),237.
2.		mmo-omi 50 mg/L		GENTAE    Genetics. 90 (1978),1.
3.		mmo-sat 200 mg/L		JOBAAY    Journal of Bacteriology. 122 (1975),549.
4.		mnt-mus-ipr 280 µmol/kg		MUREAV    Mutation Research. 26 (1974),553.
5.		dns-mam:lym 1 µmol/L		CBINA8    Chemico-Biological Interactions. 8 (1974),113.
6.		orl-mus LD50:1320 mg/kg		FAZMAE    Fortschritte der Arzneimittelforschung. 17 (1973),108.
7.		scu-mus LD50:239 mg/kg		JPETAB    Journal of Pharmacology and Experimental Therapeutics. 119 (1957),444.
8.		ivn-mus LD50:50 mg/kg		THERAP    Therapie. 25 (1970),823.
9.		orl-ckn LD50:714 mg/kg		AEPPAE    Naunyn-Schmiedeberg’s Archiv fuer Experimentelle Pathologie und Pharmakologie. 201 (1943),402.