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3H-1,2,4-Triazol-3-one,2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)- cas no:83366-66-9

Synonyms: Nefazodone

Identification
Name3H-1,2,4-Triazol-3-one,2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-
CAS83366-66-9
SynonymsNefazodone
Molecular FormulaC25H32 Cl N5 O2
Molecular Weight470.01
Chemical Properties
AppearanceWhite to off-white crystalline powder
Safety Data

Hazard UN NO.
Safety

Safety Information of Nefazodone hydrochloride (83366-66-9):
Safety Statements: 22-24/25
22: Do not breathe dust 
24/25: Avoid contact with skin and eyes 
WGK Germany: 3
 
 


Toxicity

The toxicity of Nefazodone hydrochloride (83366-66-9):

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo oral 40mg/kg/2W-I (40mg/kg) PERIPHERAL NERVE AND SENSATION: PARESTHESIS Journal of Clinical Psychiatry. Vol. 61, Pg. 216, 2000.
 
women TDLo oral 28mg/kg/1W-I (28mg/kg) BEHAVIORAL: TOXIC PSYCHOSIS
BEHAVIORAL: EXCITEMENT
BEHAVIORAL: ALTERATION OF OPERANT CONDITIONING
American Journal of Psychiatry. Vol. 154, Pg. 578, 1997.

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