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Home > products > Acetic acid,2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride(1:2)

Acetic acid,2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride(1:2) cas no:83881-52-1

Synonyms: Alercet;Alerid;Alerlisin;Cesta;Cetirizinedihydrochloride;Cetirizine hydrochloride;Cetrak;Cetrine;Cetrizet;Epirizine;Formistin;Histazine-1;P 071;Reactine;Riztec;Ryzen;Triz;UCB-P 071;Virlix;Zirtec;Zirtek;Zirtin;Zyrlex;Zyrtec;Zyrzine;

Identification
NameAcetic acid,2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-, hydrochloride(1:2)
CAS83881-52-1
SynonymsAlercet;Alerid;Alerlisin;Cesta;Cetirizinedihydrochloride;Cetirizine hydrochloride;Cetrak;Cetrine;Cetrizet;Epirizine;Formistin;Histazine-1;P 071;Reactine;Riztec;Ryzen;Triz;UCB-P 071;Virlix;Zirtec;Zirtek;Zirtin;Zyrlex;Zyrtec;Zyrzine;
Molecular FormulaC21H25ClN2O3.2(HCl)
Molecular Weight461.80968
Chemical Properties
AppearanceA 5% w/v solution(solution S)in water is not more intensely
storage tempDesiccate at RT
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety Data

Hazard Xn: Harmful;
Risk R22
Safety

Hazard Codes :?HarmfulXn,IrritantXi
Risk Statements : 22-36/37/38?
R22:Harmful if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements : 26-36?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.
RIDADR : 3249
WGK Germany : 3
RTECS : AG0977500
HazardClass : 6.1(b)
PackingGroup : III


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral > 320mg/kg (320mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

GASTROINTESTINAL: NAUSEA OR VOMITING
Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 1859, 1994.
mouse LDLo intraperitoneal 138mg/kg (138mg/kg) ? United States Patent Document. Vol. #4525358,
rat LD50 oral 365mg/kg (365mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Kiso to Rinsho. Clinical Report. Vol. 28, Pg. 1859, 1994.

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Zhejiang Zhebei Pharmaceutical Co., Ltd.
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Address: Sanlitang, Qianyuan Town, Deqing, Zhejiang 313216,

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