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Mometasone furoate cas no:83919-23-7

Synonyms: Elocon (TN);Rimelon;Ecural;9,21-Dichloro-11beta,17-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 17-(2-furoate);Nosorex;Sch 32088;[(9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate;Elocone;Mometasone furoate [USAN:JAN];Pregna-1,4-diene-3,20-dione,9,21-dichloro- 17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16- methyl-,(11a,16R)-;Danitin;Elocon;Mometasone furoate (JAN/USP);Flumeta;Nasonex;

Identification
NameMometasone furoate
CAS83919-23-7
SynonymsElocon (TN);Rimelon;Ecural;9,21-Dichloro-11beta,17-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 17-(2-furoate);Nosorex;Sch 32088;[(9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate;Elocone;Mometasone furoate [USAN:JAN];Pregna-1,4-diene-3,20-dione,9,21-dichloro- 17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16- methyl-,(11a,16R)-;Danitin;Elocon;Mometasone furoate (JAN/USP);Flumeta;Nasonex;
Molecular FormulaC27H30Cl2O6
Molecular Weight521.44
Chemical Properties
AppearanceDistributed as 0.1% ointment with a petrolatum base.
refractive index1.604
storage tempKeep container tightly sealed. Store in cool, dry conditions in well sealed containers.
Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LDLo subcutaneous 1gm/kg (1000mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 24, Pg. 4203, 1990.
rat LD50 subcutaneous 300mg/kg (300mg/kg) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Kiso to Rinsho. Clinical Report. Vol. 24, Pg. 4203, 1990.

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