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10H-Phenothiazine,10-[2-(1-pyrrolidinyl)ethyl]- cas no:84-08-2

Synonyms: Phenothiazine,10-[2-(1-pyrrolidinyl)ethyl]- (6CI,8CI);10-[2-(1-Pyrrolidinyl)ethyl]phenothiazine; N-(b-Pyrrolidinoethyl)phenothiazine; Parathiazine (DCI);Parathiazine (pharmaceutical); Pyrathiazine; Pyrrolidine,1-(2-phenothiazin-10-ylethyl)-; Pyrrolidine,1-[2-(10H-phenothiazin-10-yl)ethyl]-

Identification
Name10H-Phenothiazine,10-[2-(1-pyrrolidinyl)ethyl]-
CAS84-08-2
SynonymsPhenothiazine,10-[2-(1-pyrrolidinyl)ethyl]- (6CI,8CI);10-[2-(1-Pyrrolidinyl)ethyl]phenothiazine; N-(b-Pyrrolidinoethyl)phenothiazine; Parathiazine (DCI);Parathiazine (pharmaceutical); Pyrathiazine; Pyrrolidine,1-(2-phenothiazin-10-ylethyl)-; Pyrrolidine,1-[2-(10H-phenothiazin-10-yl)ethyl]-
Molecular FormulaC18H20 N2 S
Molecular Weight296.46
Chemical Properties
refractive index1.641
Safety Data

Safety

Poison by intraperitoneal route. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NOx and SOx.


Toxicity

Toxic information about Parathiazine (CAS NO.84-08-2) is:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 190mg/kg (190mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 237, 1957.
mouse LD50 oral 707mg/kg (707mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 237, 1957.
mouse LD50 subcutaneous 1500mg/kg (1500mg/kg)   "Burger's Medicinal Chemistry," 4th ed., Wolff, M.E., ed., New York, John Wiley & Sons, Inc., 1980Vol. 4(3), Pg. 569, 1980.

 

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