Yohimban-16-carboxylicacid, 18-[[4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxy-,methyl ester, (3b,16b,17a,18b,20a)- cas no:84-36-6
Synonyms: 3b,20a-Yohimban-16b-carboxylic acid, 18b-hydroxy-11,17a-dimethoxy-, methyl ester,4-hydroxy-3,5-dimethoxybenzoate (ester) ethyl carbonate (ester) (8CI); Reserpicacid, methyl ester, ester with syringic acid, ethyl carbonate (6CI);Carbethoxysyringoyl methylreserpate; Isotense; Londomin; Methylcarbethoxysyringoyl reserpate; Methyl reserpate ester of syringic acid ethylcarbonate; NSC 77030; Raunova; Seniramin; Singoserp; Siringina; Su 3118;Syringic acid ethyl carbonate ester with methyl reserpate; Syringopine;Syrosingopin; Syrosingopine
NameYohimban-16-carboxylicacid, 18-[[4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxy-,methyl ester, (3b,16b,17a,18b,20a)-
CAS84-36-6
Synonyms3b,20a-Yohimban-16b-carboxylic acid, 18b-hydroxy-11,17a-dimethoxy-, methyl ester,4-hydroxy-3,5-dimethoxybenzoate (ester) ethyl carbonate (ester) (8CI); Reserpicacid, methyl ester, ester with syringic acid, ethyl carbonate (6CI);Carbethoxysyringoyl methylreserpate; Isotense; Londomin; Methylcarbethoxysyringoyl reserpate; Methyl reserpate ester of syringic acid ethylcarbonate; NSC 77030; Raunova; Seniramin; Singoserp; Siringina; Su 3118;Syringic acid ethyl carbonate ester with methyl reserpate; Syringopine;Syrosingopin; Syrosingopine
EINECS(EC#)201-527-0
Molecular FormulaC35H42 N2 O11
Molecular Weight666.79
refractive index1.615
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(b)
Safety
Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition Syrosingopine (CAS NO.84-36-6) emits toxic fumes of NOx.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LD50 |
intraperitoneal |
101mg/kg (101mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 365, 1982. |
| mouse |
LD50 |
oral |
1293mg/kg (1293mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 365, 1982. |
| mouse |
LD50 |
subcutaneous |
281mg/kg (281mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 365, 1982. |
| rat |
LD50 |
intraperitoneal |
286mg/kg (286mg/kg) |
|
Drugs in Japan Vol. 6, Pg. 365, 1982. |
| rat |
LD50 |
intravenous |
50mg/kg (50mg/kg) |
|
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 119, Pg. 245, 1959. |
| rat |
LD50 |
oral |
> 2gm/kg (2000mg/kg) |
|
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 386, 1975. |
| rat |
LD50 |
subcutaneous |
> 2gm/kg (2000mg/kg) |
|
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 6, Pg. 386, 1975. |
