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1,4-Naphthalenedione,2-hydroxy-3-(3-methyl-2-buten-1-yl)- cas no:84-79-7

Synonyms: 1,4-Naphthalenedione,2-hydroxy-3-(3-methyl-2-butenyl)- (9CI); 1,4-Naphthoquinone,2-hydroxy-3-(3-methyl-2-butenyl)- (7CI,8CI); Lapachol (6CI);2-Hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthalenedione;2-Hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone; Bethabarra Wood; C.I.75490; C.I. Natural Yellow 16; Greenhartin; Ipe-tobacco Wood; Lapachol Wood;NSC 11905; NSC 629756; Surinam Greenheart Wood; Taigu Wood; Taiguic acid;Tecomin

Identification
Name1,4-Naphthalenedione,2-hydroxy-3-(3-methyl-2-buten-1-yl)-
CAS84-79-7
Synonyms1,4-Naphthalenedione,2-hydroxy-3-(3-methyl-2-butenyl)- (9CI); 1,4-Naphthoquinone,2-hydroxy-3-(3-methyl-2-butenyl)- (7CI,8CI); Lapachol (6CI);2-Hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthalenedione;2-Hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone; Bethabarra Wood; C.I.75490; C.I. Natural Yellow 16; Greenhartin; Ipe-tobacco Wood; Lapachol Wood;NSC 11905; NSC 629756; Surinam Greenheart Wood; Taigu Wood; Taiguic acid;Tecomin
EINECS(EC#)201-563-7
Molecular FormulaC15H14 O3
Molecular Weight242.29
Chemical Properties
Appearancewhite to yellow powder
refractive index1.606
Safety Data

Hazard Xn: Harmful;
Risk R20/21/22
Safety

Safety Information of Lapachol (CAS NO.84-79-7):
Hazard Codes: Xn Harmful
Risk Statements: 20/21/22-36/37/38
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed
R36/37/38:Irritating to eyes, respiratory system and skin
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36:Wear suitable protective clothing
WGK Germany: 3
RTECS: QL8750000
Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and fumes.


Toxicity
1.    

orl-rat LDLo:1200 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 17 (1970),1.
2.    

orl-mus LD50:487 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 17 (1970),1.
3.    

ipr-mus LD50:400 mg/kg

    JMCMAR    Journal of Medicinal Chemistry. 26 (1983),570.

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