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10H-Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]- cas no:84-97-9

Synonyms: Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]- (6CI,7CI,8CI);10-(3-Methylpiperazinopropyl)phenothiazine; 10-(g-Methylpiperazinopropyl)phenothiazine;10-[3-(1-Methylpiperazin-4-yl)propyl]phenothiazine;10-[3-(4-Methyl-1-piperazinyl)propyl]phenothiazine;10-[3-(4-Methylpiperazinyl)propyl]phenothiazine; NSC 638694; P 725; Perazine;Pernazine; Psytomin; Taxilan

Identification
Name10H-Phenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]-
CAS84-97-9
SynonymsPhenothiazine,10-[3-(4-methyl-1-piperazinyl)propyl]- (6CI,7CI,8CI);10-(3-Methylpiperazinopropyl)phenothiazine; 10-(g-Methylpiperazinopropyl)phenothiazine;10-[3-(1-Methylpiperazin-4-yl)propyl]phenothiazine;10-[3-(4-Methyl-1-piperazinyl)propyl]phenothiazine;10-[3-(4-Methylpiperazinyl)propyl]phenothiazine; NSC 638694; P 725; Perazine;Pernazine; Psytomin; Taxilan
EINECS(EC#)201-578-9
Molecular FormulaC20H25 N3 S
Molecular Weight339.54
Chemical Properties
refractive index1.615
Safety Data

Safety

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. Human toxic effects by unspecified route. When heated to decomposition it emits very toxic fumes of NOx and SOx.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human TDLo unreported 270mg/kg/28D (270mg/kg) behavioral: somnolence (general depressed activity) behavioral: ataxia Arzneimittel-Forschung. Drug Research. Vol. 32, Pg. 911, 1982.
mouse LD50 intraperitoneal 185mg/kg (185mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 199, 1958.
mouse LD50 intravenous 75mg/kg (75mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 199, 1958.
mouse LD50 oral 640mg/kg (640mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 199, 1958.
mouse LD50 subcutaneous 560mg/kg (560mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 199, 1958.
rabbit LD50 intravenous 25mg/kg (25mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 199, 1958.
rat LD50 intraperitoneal 300mg/kg (300mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 199, 1958.
rat LD50 intravenous 80mg/kg (80mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 199, 1958.
rat LD50 oral 500mg/kg (500mg/kg) behavioral: convulsions or effect on seizure threshold Archives Internationales de Pharmacodynamie et de Therapie. Vol. 115, Pg. 1, 1958.

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