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Phthalic anhydride cas no:85-44-9

Synonyms: 2,5-Isobenzofurandione; Phthalic anhydride 99+ %; 2-benzofuran-1,3-dione

Identification
NamePhthalic anhydride
CAS85-44-9
Synonyms2,5-Isobenzofurandione; Phthalic anhydride 99+ %; 2-benzofuran-1,3-dione
EINECS(EC#)201-607-5
Molecular FormulaC8H4O3
Molecular Weight148.12
Chemical Properties
Appearancewhite crystalline solid with choking odour
refractive index1.646
storage tempStore at RT.
Sensitive Moisture Sensitive
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass8
Safety Data

Hazard Xn:Harmful
Risk R22;R37/38;R41;R42/43
Safety

Hazard Codes: Xn
Risk Statements: 22-37/38-41-42/43
22:? Harmful if swallowed?
37/38:? Irritating to respiratory system and skin?
41:? Risk of serious damage to eyes?
42/43:? May cause sensitization by inhalation and skin contact
Safety Statements: 23-24/25-26-37/39-46-22
23:? Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer)?
24/25:? Avoid contact with skin and eyes?
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
37/39:? Wear suitable gloves and eye/face protection?
46:? If swallowed, seek medical advice immediately and show this container or label?
22:? Do not breathe dust??
RIDADR: 2214
WGK Germany: 1
F: 10-21: Keep under argon. Sensitive to humidity.
HazardClass: 8
PackingGroup: III
Poison by ingestion. Experimental teratogenic effects. A corrosive eye, skin, and mucous membrane irritant. A common air contaminant. Combustible when exposed to heat or flame; can react with oxidizing materials. Moderate explosion hazard in the form of dust when exposed to flame.


Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 oral 800mg/kg (800mg/kg) ? "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 322, 1986.
guinea pig LD50 intraperitoneal 100mg/kg (100mg/kg) ? "Practical Toxicology of Plastics," Lefaux, R., Cleveland, OH, Chemical Rubber Co., 1968Vol. -, Pg. 410, 1968.
mouse LD50 oral 1500mg/kg (1500mg/kg) ? "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 100, 1982.
rabbit LD50 skin > 10gm/kg (10000mg/kg) ? BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 13-4/1970,
rat LC50 inhalation > 210mg/m3/1H (210mg/m3) ? BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 13-4/1970,
rat LD50 oral 1530mg/kg (1530mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 15(Suppl,

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