Temozolomide cas no:85622-93-1
Synonyms: 3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide;CCRG 81045;Temozolodida [Spanish];Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3, 4-dihydro-3-methyl-4-oxo-;Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide,3,4-dihydro-3-methyl-4-oxo-;3-methyl-2-oxo-1,3,4,5,8-pentazabicyclo[4.3.0]nona-4,6,8-triene-7-carboxamide;MB 39831;Methazolastone;Temozolomide [BAN:INN];Imidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo-;Temodal;3-Methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide;Temozolomidum [Latin];8-Carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one;
NameTemozolomide
CAS85622-93-1
Synonyms3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide;CCRG 81045;Temozolodida [Spanish];Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3, 4-dihydro-3-methyl-4-oxo-;Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide,3,4-dihydro-3-methyl-4-oxo-;3-methyl-2-oxo-1,3,4,5,8-pentazabicyclo[4.3.0]nona-4,6,8-triene-7-carboxamide;MB 39831;Methazolastone;Temozolomide [BAN:INN];Imidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo-;Temodal;3-Methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide;Temozolomidum [Latin];8-Carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one;
Molecular FormulaC6H6N6O2
Molecular Weight194.15
AppearanceOff-White to Light-Pink Crystalline Solid
storage temp2-8°C
Hazard T: Toxic;Xi: Irritant;
Risk R45
Safety
Safety Information about?Temozolomide (CAS NO.85622-93-1):
Hazard Codes:?
T,?
Xi
The Risk Statements: 45-46-60-61-22-36/37/38
45:?May cause cancer?
46: May cause heritable genetic damage?
60:?May impair fertility?
61:?May cause harm to the unborn child?
36/37/38:?Irritating to eyes, respiratory system and skin?
The Safety Statements:?24/25-45-36/37-26-53
26:?In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
45:?In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)??
53:?Avoid exposure - obtain special instruction before use?
24/25:?Avoid contact with skin and eyes?
36/37:?Wear suitable protective clothing and gloves?
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| mouse |
LDLo |
intraperitoneal |
125mg/kg (125mg/kg) |
? |
Cancer Research. Vol. 47, Pg. 5846, 1987. |
