Acridinium,3,6-diamino-10-methyl-, chloride (1:1) cas no:86-40-8

NameAcridinium,3,6-diamino-10-methyl-, chloride (1:1)
CAS86-40-8
Synonyms3,6-Diamino-10-methylacridiniumchloride (7CI); Acridinium, 3,6-diamino-10-methyl-, chloride (8CI,9CI); 2,8-Diamino-10-methylacridiniumchloride; 3,6-Diamino-N-methylacridinium chloride; Avlon; Burnol; C.I. 46000;Chromoflavine
EINECS(EC#)201-668-8
Molecular FormulaC14H14 N3 . Cl
Molecular Weight259.76

Safety

A human poison by intravenous route. Poison experimentally by intraperitoneal, intravenous, and subcutaneous routes. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NO_x and Cl⁻.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD50	oral	56200ug/kg (56.2mg/kg)		Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
cat	LDLo	intravenous	7353ug/kg (7.353mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Lancet. Vol. 196, Pg. 838, 1919.
dog	LDLo	intravenous	25mg/kg (25mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of Pharmacology and Experimental Therapeutics. Vol. 38, Pg. 145, 1930.
frog	LDLo	subcutaneous	800mg/kg (800mg/kg)	PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE CARDIAC: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 12, Pg. 195, 1921.
guinea pig	LDLo	intraperitoneal	250mg/kg (250mg/kg)		"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1292, 1935.
guinea pig	LDLo	intravenous	40mg/kg (40mg/kg)		"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1292, 1935.
guinea pig	LDLo	subcutaneous	250mg/kg (250mg/kg)		"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1292, 1935.
human	LDLo	intravenous	1500ug/kg (1.5mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 38, Pg. 145, 1930.
mammal (species unspecified)	LD50	intraperitoneal	65mg/kg (65mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 80, Pg. 217, 1944.
mouse	LD50	intravenous	40mg/kg (40mg/kg)		British Journal of Experimental Pathology. Vol. 28, Pg. 1, 1947.
mouse	LD50	subcutaneous	14mg/kg (14mg/kg)		British Journal of Experimental Pathology. Vol. 28, Pg. 1, 1947.
mouse	LDLo	intraperitoneal	11mg/kg (11mg/kg)		Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972.
quail	LD50	oral	> 100mg/kg (100mg/kg)		Ecotoxicology and Environmental Safety. Vol. 6, Pg. 149, 1982.
rabbit	LDLo	intravenous	25mg/kg (25mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of Pharmacology and Experimental Therapeutics. Vol. 38, Pg. 145, 1930.