863-61-6|MenatetrenoneProducts Supply - Chemical intermediates Network

Menatetrenone cas no:863-61-6

Synonyms: Vitamin K2(mk-4);1,4-Naphthalenedione,2-methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-, (E,E,E)-;1,4-Naphthalenedione,2-methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl]-(9CI);2-Methyl-3-geranylgeranyl-1,4-naphthoquinone;Glakay;Kaytwo;MK4;Menaquinone4;Menaquinone K4;Vitamin K2(20);Vitamin MK 4;

Identification

NameMenatetrenone
CAS863-61-6
SynonymsVitamin K2(mk-4);1,4-Naphthalenedione,2-methyl-3-(3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl)-, (E,E,E)-;1,4-Naphthalenedione,2-methyl-3-[(2E,6E,10E)-3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenyl]-(9CI);2-Methyl-3-geranylgeranyl-1,4-naphthoquinone;Glakay;Kaytwo;MK4;Menaquinone4;Menaquinone K4;Vitamin K2(20);Vitamin MK 4;
Molecular FormulaC₃₁H₄₀O₂
Molecular Weight444.71

Chemical Properties

Appearanceyellow crystals
refractive index1.538
storage temp?20°C

Safety Data

Safety

Safety Statements: 22-24/25?
S22:Do not breathe dust.?
S24/25:Avoid contact with skin and eyes.
WGK Germany: 3
RTECS: QL9279500
An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes.

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD	oral	> 1gm/kg (1000mg/kg)	?	Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 445, 1971.
dog	LD	unreported	> 3gm/kg (3000mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 37, Pg. 2518, 1995.
dog	LD50	intravenous	> 40mL/kg (40mL/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BLOOD: PIGMENTED OR NUCLEATED RED BLLOD CELLS	Kiso to Rinsho. Clinical Report. Vol. 25, Pg. 2003, 1991.
monkey	LD50	intravenous	> 10mL/kg (10mL/kg)	BLOOD: CHANGES IN CELL COUNT (UNSPECIFIED)	Kiso to Rinsho. Clinical Report. Vol. 25, Pg. 2003, 1991.
mouse	LD	oral	> 5mg/kg (5mg/kg)	?	Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 445, 1971.
mouse	LD50	intravenous	> 40mL/kg (40mL/kg)	SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Kiso to Rinsho. Clinical Report. Vol. 25, Pg. 2003, 1991.
mouse	LDLo	intraperitoneal	5gm/kg (5000mg/kg)	?	Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 445, 1971.
mouse	LDLo	subcutaneous	5gm/kg (5000mg/kg)	?	Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 445, 1971.
rabbit	LD	intravenous	> 100mg/kg (100mg/kg)	?	Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 461, 1971.
rabbit	LDLo	subcutaneous	100mg/kg (100mg/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 461, 1971.
rat	LD	oral	> 5gm/kg (5000mg/kg)	?	Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 445, 1971.
rat	LD	subcutaneous	> 5gm/kg (5000mg/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 445, 1971.
rat	LD50	intravenous	> 40mL/kg (40mL/kg)	SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Kiso to Rinsho. Clinical Report. Vol. 25, Pg. 2003, 1991.
rat	LDLo	intraperitoneal	5gm/kg (5000mg/kg)	?	Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 445, 1971.

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Menatetrenone cas no:863-61-6

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