Yohimban-16-carboxylicacid, 10,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3b,16b,17a,18b,20a)- cas no:865-04-3

Synonyms: 3b,20a-Yohimban-16b-carboxylic acid, 18b-hydroxy-10,17a-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate(ester) (8CI); Deserpidine, 10-methoxy- (6CI,7CI);Benz[g]indolo[2,3-a]quinolizine, yohimban-16-carboxylic acid deriv.;(-)-10-Methoxydeserpidine; 10-MD; 10-Methoxydeserpidine; Deaserpyl; Decaserpil;Decaserpin; Decaserpine; Decaserpyl; Decoserpyl; Methoserpidine; Minoran; NSC169423; Neoserpin; Resertene; Tenserpina

Identification

NameYohimban-16-carboxylicacid, 10,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3b,16b,17a,18b,20a)-
CAS865-04-3
Synonyms3b,20a-Yohimban-16b-carboxylic acid, 18b-hydroxy-10,17a-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate(ester) (8CI); Deserpidine, 10-methoxy- (6CI,7CI);Benz[g]indolo[2,3-a]quinolizine, yohimban-16-carboxylic acid deriv.;(-)-10-Methoxydeserpidine; 10-MD; 10-Methoxydeserpidine; Deaserpyl; Decaserpil;Decaserpin; Decaserpine; Decaserpyl; Decoserpyl; Methoserpidine; Minoran; NSC169423; Neoserpin; Resertene; Tenserpina
EINECS(EC#)212-733-5
Molecular FormulaC33H40 N2 O9
Molecular Weight608.75

Chemical Properties

refractive index1.619

Safety Data

Safety

Poison by intraperitoneal and intravenous routes. Questionable human carcinogen producing colon, nose, and skin tumors. When heated to decomposition it emits toxic fumes of NO_x.

Toxicity

1.	ipr-mus LD50:82 mg/kg	JPPMAB Journal of Pharmacy and Pharmacology. 12 (1960),677.
2.	ivn-mus LD50:8750 µg/kg	ARZNAD Arzneimittel-Forschung. Drug Research. 14 (1964),1040.
3.	ivn-gpg LDLo:52 mg/kg	THERAP Therapie. 15 (1960),663.

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