865-21-4|vinblastineProducts Supply - Chemical intermediates Network

vinblastine cas no:865-21-4

Synonyms: Vincaleukoblastine;

Identification

Namevinblastine
CAS865-21-4
SynonymsVincaleukoblastine;
EINECS(EC#)212-734-0
Molecular FormulaC46H58N4O9
Molecular Weight810.9856

Chemical Properties

AppearancePOWDER

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass6.1(a)

Safety Data

Safety

Human poison by intravenous route. Experimental poison by intraperitoneal route. Human systemic effects by intravenous and ocular routes: visual field changes, conjunctiva irritation and other eye effects, cardiomyopathy including infarction, and changes in bone marrow. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO_x. Used as an antineoplastic agent. See also VINCALEUKOBLASTINE SULFATE (1:1) (SALT).
RIDADR: 1544
HazardClass: 6.1(a)
PackingGroup: II

Toxicity

1.	dni-hmn:oth 200 µg/L	26QZAP Advances in Antimicrobial and Antineoplastic Chemotherapy, Progress in Research and Clinical Application. 2 (1972),377.
2.	cyt-mus-ipr 900 µg/kg	ENMUDM Environmental Mutagenesis. 8 (1986),273.
3.	ivn-man LDLo:2319 µg/kg/38W-I:CVS	LANCAO Lancet. 2 (1980),692.
4.	ocu-hmn TDLo:14 µg/kg:EYE	BJOPAL British Journal of Ophthalmology. 62 (1978),97.
5.	unr-man TDLo:80 µg/kg:BLD	CCROBU Cancer Chemotherapy Reports, Part 1. 50 (1966),219.
6.	ipr-rat LD50:1 mg/kg	VINIT* Vsesoyuznyi Institut Nauchnoi i Tekhnicheskoi Informatsii (VINITI). All-Union Institute of Scientific and Technical Information. (Moscow, USSR) #3713-83 .

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Shanghai Domen International Co., Ltd: Tel:; Address: Rm1907, Bldg A, No.1088 Xinjinqiao Rd, Pudong, Shanghai, China

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Changzhou VX Chemicals Co., Ltd.: Tel:+86-(519)-86011997; Address: No.5 Binjiang Road, Jiangbian Chemical Park, Xinbei District, Changzhou, Jiangsu 213033,

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shanghai Tauto Biotech Co., Ltd: Tel:86-21-51320588; Address: No. 326, Aidisheng Rd , Zhangjiang Hi-tech Park, Shanghai , P.R.CHINA

WuXi AppTec (Tianjin) Co,. Ltd.: Tel:86-22-59863146; Address: 111 HuangHai Road TEDA Tianjin, P. R. China

vinblastine cas no:865-21-4

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