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vinblastine cas no:865-21-4

Synonyms: Vincaleukoblastine;

Identification
Namevinblastine
CAS865-21-4
SynonymsVincaleukoblastine;
EINECS(EC#)212-734-0
Molecular FormulaC46H58N4O9
Molecular Weight810.9856
Chemical Properties
AppearancePOWDER
Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)
Hazardclass6.1(a)
Safety Data

Safety

Human poison by intravenous route. Experimental poison by intraperitoneal route. Human systemic effects by intravenous and ocular routes: visual field changes, conjunctiva irritation and other eye effects, cardiomyopathy including infarction, and changes in bone marrow. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. Used as an antineoplastic agent. See also VINCALEUKOBLASTINE SULFATE (1:1) (SALT).
RIDADR: 1544
HazardClass: 6.1(a)
PackingGroup: II


Toxicity
1.    

dni-hmn:oth 200 µg/L

    26QZAP    Advances in Antimicrobial and Antineoplastic Chemotherapy, Progress in Research and Clinical Application. 2 (1972),377.
2.    

cyt-mus-ipr 900 µg/kg

    ENMUDM    Environmental Mutagenesis. 8 (1986),273.
3.    

ivn-man LDLo:2319 µg/kg/38W-I:CVS

    LANCAO    Lancet. 2 (1980),692.
4.    

ocu-hmn TDLo:14 µg/kg:EYE

    BJOPAL    British Journal of Ophthalmology. 62 (1978),97.
5.    

unr-man TDLo:80 µg/kg:BLD

    CCROBU    Cancer Chemotherapy Reports, Part 1. 50 (1966),219.
6.    

ipr-rat LD50:1 mg/kg

    VINIT*    Vsesoyuznyi Institut Nauchnoi i Tekhnicheskoi Informatsii (VINITI). All-Union Institute of Scientific and Technical Information. (Moscow, USSR) #3713-83 .

supplier list

Changzhou Leo Chemical Co.,Ltd.
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Southern Herbals Ltd.
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Aceto Corporation
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Austin Chemical Company, Inc.
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Sino-Future Bio-tech Co., Ltd.
Tel:+86-(29)-83182005
Address: No. 18, Dianzi 1Road, Xi'an, Shaanxi 710014,
Hunan Keyuan Bio-products Co.,Ltd
Tel:+86-(21)-58341647
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Hangzhou Kinsey Bio-tech Co., Ltd
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Address: 1207, Taihe International Mansion, No.1 Building 168 Chaohui Road, Hangzhou, Zhejiang,
Changzhou VX Chemicals Co., Ltd.
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Address: No.5 Binjiang Road, Jiangbian Chemical Park, Xinbei District, Changzhou, Jiangsu 213033,
Varda Biotech Pvt. Ltd.
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VINS Bioproducts Ltd.
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Address: 806, Essjay House, Road No: 3 Banjara Hills, Hyderabad, Andhra Pradesh 500 034,
Vinkem Labs Private Limited
Tel:+91-(44)-26201796
Address: AH - 29, Shanthi Colony, Anna Nagar, Chennai, Tamil Nadu 600 040,
Tecoland Corporation
Tel:+1-(732)-603-9577
Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428,
Facus Pharmaceutical Co., Ltd.
Tel:+86-(574)-6237-8411
Address: 24Fl, Yuanjing Building, Beilun, Ningbo, Zhejiang 315800,
KINFON Pharmaceutical and Chemical Service
Tel:+86-(21)-58871570
Address: No.331, Dongyuan San Cun, 978# of Pudong South Rd., Shanghai 200120,

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