Urea,N-butyl-N-nitroso- cas no:869-01-2

Synonyms: Urea,1-butyl-1-nitroso- (7CI,8CI); 1-Butyl-1-nitrosourea; N-Butyl-N-nitrosourea;N-Nitroso-N-butylurea; N-Nitroso-N-n-butylurea; N-n-Butyl-N-nitrosourea; NSC45639

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Identification
Chemical Properties
Safety Data
Toxicity

Identification

NameUrea,N-butyl-N-nitroso-
CAS869-01-2
SynonymsUrea,1-butyl-1-nitroso- (7CI,8CI); 1-Butyl-1-nitrosourea; N-Butyl-N-nitrosourea;N-Nitroso-N-butylurea; N-Nitroso-N-n-butylurea; N-n-Butyl-N-nitrosourea; NSC45639
Molecular FormulaC5H11 N3 O2
Molecular Weight145.19

Chemical Properties

refractive index1.518

Safety Data

Safety

The safety information of N-Nitroso-N-butylurea (CAS NO.869-01-2):
Suspected carcinogen with experimental carcinogenic and tumorigenic data. A poison by ingestion. Moderately toxic by subcutaneous route. Experimental teratogenic and reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x. See also NITROSAMINES.

Toxicity

The toxicity of N-Nitroso-N-butylurea (CAS NO.869-01-2):

1.	pic-esc 2 mg/L	TCMUE9 Topics in Chemical Mutagenesis. 1 (1984),91.
2.	sce-ham:fbr 500 µmol/L	CNREA8 Cancer Research. 44 (1984),3270.
3.	orl-rat TDLo:120 mg/kg (22D preg):ETA,TER	ARGEAR Archiv fuer Geschwulstforschung. 48 (1978),9.
4.	orl-rat TDLo:16,512 mg/kg/50W-I:CAR,REP	JCROD7 Journal of Cancer Research and Clinical Oncology. 107 (1984),32.
5.	ipr-rat TDLo:120 mg/kg (22D preg):ETA,TER	ARGEAR Archiv fuer Geschwulstforschung. 48 (1978),9.
6.	orl-rat LD₅₀:400 mg/kg	PPTCBY Proceedings of the International Symposium of the Princess Takamatsu Cancer Research Fund. (Japan Scientific Societies Press, 2-10, Hongo 6-chome, Bunkyo-ku, Tokyo 113, Japan) 2 (1972),73.
7.	scu-rat LD₅₀:1200 mg/kg	ZEKBAI Zeitschrift fuer Krebsforschung. 69 (1967),103.

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