1,3-Benzenedicarboxamide, N,N'-bis(2,3-dihydroxypropyl)-5-((hydroxyacetyl)(2-hydroxyethyl)amino)-2,4,6-triiodo- cas no:87771-40-2
Synonyms: 1,3-Benzenedicarboxamide,N,N'-bis(2,3-dihydroxypropyl)-5-[(hydroxyacetyl)(2-hydroxyethyl)amino]-2,4,6-triiodo-(9CI);Ioversol;MP 328;Optiray;Optiray 320;
Name1,3-Benzenedicarboxamide, N,N'-bis(2,3-dihydroxypropyl)-5-((hydroxyacetyl)(2-hydroxyethyl)amino)-2,4,6-triiodo-
CAS87771-40-2
Synonyms1,3-Benzenedicarboxamide,N,N'-bis(2,3-dihydroxypropyl)-5-[(hydroxyacetyl)(2-hydroxyethyl)amino]-2,4,6-triiodo-(9CI);Ioversol;MP 328;Optiray;Optiray 320;
Molecular FormulaC18H24I3N3O9
Molecular Weight807.11
AppearanceOdorless white powder.
refractive index1.738
storage tempKeep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage.
| Organism |
Test Type |
Route |
Reported Dose (Normalized Dose) |
Effect |
Source |
| dog |
LDLo |
intracrebral |
240mg/kg (240mg/kg) |
|
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 34, Pg. 1777, 1992. |
| dog |
LDLo |
intravenous |
12gm/kg (12000mg/kg) |
|
Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 34, Pg. 1777, 1992. |
| mouse |
LD50 |
intravenous |
38372mg/kg (38372mg/kg) |
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
LIVER: OTHER CHANGES
KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" |
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 20, Pg. 1127, 1992. |
| rat |
LD50 |
intracrebral |
1314mg/kg (1314mg/kg) |
|
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 22, Pg. 769, 1994. |
| rat |
LD50 |
intravenous |
21200mg/kg (21200mg/kg) |
|
Arzneimittel-Forschung. Drug Research. Vol. 44, Pg. 1275, 1994.
Link to PubMed |
| rat |
LD50 |
parenteral |
833mg/kg (833mg/kg) |
|
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 22, Pg. 769, 1994. |
