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1,2-Propanediol,3-(4-chlorophenoxy)-, 1-carbamate cas no:886-74-8

Synonyms: 1,2-Propanediol,3-(p-chlorophenoxy)-, 1-carbamate (8CI); Carbamic acid,3-(p-chlorophenoxy)-2-hydroxypropyl ester (7CI);3-(4-Chlorophenoxy)-2-hydroxypropyl carbamate;3-(p-Chlorophenoxy)-2-hydroxypropyl carbamate;3-[p-Chlorophenoxy]-1,2-propanediol-1-carbamate; Chlorphenesin carbamate;Maolate; NSC 82943; Rinlaxer; U 19646; U-19,646

Identification
Name1,2-Propanediol,3-(4-chlorophenoxy)-, 1-carbamate
CAS886-74-8
Synonyms1,2-Propanediol,3-(p-chlorophenoxy)-, 1-carbamate (8CI); Carbamic acid,3-(p-chlorophenoxy)-2-hydroxypropyl ester (7CI);3-(4-Chlorophenoxy)-2-hydroxypropyl carbamate;3-(p-Chlorophenoxy)-2-hydroxypropyl carbamate;3-[p-Chlorophenoxy]-1,2-propanediol-1-carbamate; Chlorphenesin carbamate;Maolate; NSC 82943; Rinlaxer; U 19646; U-19,646
EINECS(EC#)212-954-7
Molecular FormulaC10H12 Cl N O4
Molecular Weight245.68
Chemical Properties
refractive index1.564
Safety Data

Safety

Safety Information of Chlorphenesin carbamate (CAS NO.886-74-8):
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects by ingestion: somnolence, hallucinations or distorted perceptions, and muscle weakness. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of Cl and NOx.


Toxicity
1.    

orl-hmn TDLo:23 mg/kg/D:CNS

    34ZIAG    Toxicology of Drugs and Chemicals ,Deichmann, W.B.,New York, NY.: Academic Press, Inc.,1969,171.
2.    

orl-rat LD50:632 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 10 (1970),710.
3.    

ipr-rat LD50:354 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,386.
4.    

scu-rat LD50:952 mg/kg

    OYYAA2    Oyo Yakuri. Pharmacometrics. 13 (1977),659.
5.    

ivn-rat LD50:237 mg/kg

    YKYUA6    Yakkyoku. Pharmacy. 31 (1980),363.
6.    

orl-mus LD50:741 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 10 (1979),710.
7.    

ipr-mus LD50:452 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 10 (1979),710.
8.    

scu-mus LD50:798 mg/kg

    IYKEDH    Iyakuhin Kenkyu. Study of Medical Supplies. 10 (1979),710.
9.    

ivn-mus LD50:239 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,386.

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