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Tazobactam cas no:89786-04-9

Synonyms: (2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide; 2b-[(1,2,3-triazol-1-yl)methyl]-2a-methylpenam-3a-carboxylic acid 1,1-dioxide; Tazobactam acid; (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;

Identification
NameTazobactam
CAS89786-04-9
Synonyms(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide; 2b-[(1,2,3-triazol-1-yl)methyl]-2a-methylpenam-3a-carboxylic acid 1,1-dioxide; Tazobactam acid; (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;
Molecular FormulaC10H12N4O5S
Molecular Weight300.29
Chemical Properties
AppearanceWhite or off-white powder
refractive index1.817
storage tempStore at?0-5°C
Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

Hazard Codes:?IrritantXi
Risk Statements: 36/37/38?
R36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36: Wear suitable protective clothing


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous > 5gm/kg (5000mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

KIDNEY, URETER, AND BLADDER: HEMATURIA
Journal of Toxicological Sciences. Vol. 19(Suppl,
mouse LD50 intraperitoneal > 5gm/kg (5000mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Toxicological Sciences. Vol. 19(Suppl,
mouse LD50 intravenous > 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Toxicological Sciences. Vol. 19(Suppl,
mouse LD50 oral > 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Journal of Toxicological Sciences. Vol. 19(Suppl,
mouse LD50 subcutaneous > 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Journal of Toxicological Sciences. Vol. 19(Suppl,
rat LD50 intraperitoneal > 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Journal of Toxicological Sciences. Vol. 19(Suppl,
rat LD50 intravenous > 5gm/kg (5000mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Toxicological Sciences. Vol. 19(Suppl,
rat LD50 oral > 5gm/kg (5000mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Journal of Toxicological Sciences. Vol. 19(Suppl,
rat LD50 subcutaneous > 5gm/kg (5000mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Journal of Toxicological Sciences. Vol. 19(Suppl,

low toxicity--DL50 i.p. in mice over 4,000 mg/kg

supplier list

Tianjin Harmony Technology Development Co., Ltd.
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Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China
Hangzhou ICH Imp&Exp Co.,Ltd.
Tel:86-571-89939478 89939480 89939481
Address: Room 1224,Eastcom Mansion,398 Wensan Road,Hangzhou,310013 China
SUNWELL CHEMICALS CO.,LTD.(INTERPHARMA TRADING CO...
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IFFECT CHEMPHAR CO., LTD.
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Address: 509, FuXin International Building, No.359 HongWu R
Oasischem International
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Address: Hefei New & High Technology Development Zone
Taizhou Orient Special Chemicals Co., Ltd.,
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Address: 147# Yunxi Rd,Jiaojiang,Zhejiang,China
Jingdezhen Kaimenzi Medicinal Chemistry Co.,Ltd.
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Address: No 58,ChangxiRoad,Jingdezhen City,China
Kenloon International Limited
Tel:+86-20-83313482
Address: 22C,Tower A, 339# huanshi Dong Road.Guangzhou,510095,P.R.China.
MN Pharmaceuticals
Tel:+90 212 337 3800
Address: 34349 Gayrettepe Istanbul - TURKEY
Jingdezhen Fuxiang Pharmaceutical Co.,Ltd.
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Address: No.53 Porcelain Town Arenue, Jingdezhen City, Jiangxi Province,China
Taizhou Xinyou Pharmaceutical & Chemical Co., Ltd.
Tel:+86-(576)-8517139
Address: Waisha Industrial Zone, Jiaojiang District, Taizhou, Zhejiang 318000,
Shanghai Chemhere Co., Ltd.
Tel:+86-(21)-26607989
Address: Unit 602, No.14,Ziwei Rd, Zhangjiang High-tech Park, Shanghai,
Wyeth
Tel:+1-(973)-660-5000
Address: 5 Giralda Farms, Madison, New Jersey 07940,
Taizhou Jiakang Chemical Co., Ltd.
Tel:+86-(576)-88226722
Address: Taizhou Economic Development Zone, Taizhou, Zhejiang 318000,
Changzhou VX Chemicals Co., Ltd.
Tel:+86-(519)-86011997
Address: No.5 Binjiang Road, Jiangbian Chemical Park, Xinbei District, Changzhou, Jiangsu 213033,

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