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Tazobactam cas no:89786-04-9

Synonyms: (2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide; 2b-[(1,2,3-triazol-1-yl)methyl]-2a-methylpenam-3a-carboxylic acid 1,1-dioxide; Tazobactam acid; (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;

Identification
NameTazobactam
CAS89786-04-9
Synonyms(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide; 2b-[(1,2,3-triazol-1-yl)methyl]-2a-methylpenam-3a-carboxylic acid 1,1-dioxide; Tazobactam acid; (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;
Molecular FormulaC10H12N4O5S
Molecular Weight300.29
Chemical Properties
AppearanceWhite or off-white powder
refractive index1.817
storage tempStore at?0-5°C
Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

Hazard Codes:?IrritantXi
Risk Statements: 36/37/38?
R36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36: Wear suitable protective clothing


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous > 5gm/kg (5000mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

KIDNEY, URETER, AND BLADDER: HEMATURIA
Journal of Toxicological Sciences. Vol. 19(Suppl,
mouse LD50 intraperitoneal > 5gm/kg (5000mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Toxicological Sciences. Vol. 19(Suppl,
mouse LD50 intravenous > 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Toxicological Sciences. Vol. 19(Suppl,
mouse LD50 oral > 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Journal of Toxicological Sciences. Vol. 19(Suppl,
mouse LD50 subcutaneous > 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Journal of Toxicological Sciences. Vol. 19(Suppl,
rat LD50 intraperitoneal > 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Journal of Toxicological Sciences. Vol. 19(Suppl,
rat LD50 intravenous > 5gm/kg (5000mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Toxicological Sciences. Vol. 19(Suppl,
rat LD50 oral > 5gm/kg (5000mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Journal of Toxicological Sciences. Vol. 19(Suppl,
rat LD50 subcutaneous > 5gm/kg (5000mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Journal of Toxicological Sciences. Vol. 19(Suppl,

low toxicity--DL50 i.p. in mice over 4,000 mg/kg

supplier list

Tianjin Harmony Technology Development Co., Ltd.
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Address: Room 601 of BokeBuilding, 100 Fukang Road, Tianjin, China
Hangzhou ICH Imp&Exp Co.,Ltd.
Tel:86-571-89939478 89939480 89939481
Address: Room 1224,Eastcom Mansion,398 Wensan Road,Hangzhou,310013 China
SUNWELL CHEMICALS CO.,LTD.(INTERPHARMA TRADING CO...
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Address: SUITE 1108,GOLDEN PLAZA,NO.118,QING CHUN ROAD,HANGZHOU,ZHEJIANG,CHINA
IFFECT CHEMPHAR CO., LTD.
Tel:86-25-84679300
Address: 509, FuXin International Building, No.359 HongWu R
Luna Chemicals Co.,Ltd.
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Address: 1502-1503,No.310 North Zhong Shan Rd., Hangzhou,China
Ancheng Pharma Limited
Tel:+86-755-82713308
Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China
Oasischem International
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Address: Hefei New & High Technology Development Zone
Hangzhou Cowin Pharma Co., Ltd.
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Address: B-12F,International Garden,No.158 Tianmushan Road,Hangzhou,China
Hengdian Group . / Zhejiang Hengdian Imp. & Exp. ...
Tel:+86-571-87635700
Address: 3/F, World Trade Office Plaza, World Trade Centre Zhejiang,122 Shuguang Road, Hangzhou, Zhejiang P.R China
Taizhou Orient Special Chemicals Co., Ltd.,
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Address: 147# Yunxi Rd,Jiaojiang,Zhejiang,China
Jingdezhen Kaimenzi Medicinal Chemistry Co.,Ltd.
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Address: No 58,ChangxiRoad,Jingdezhen City,China
Melone Pharmaceutical Co., Ltd.
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Address: Room 2209锛孨o.232, Jinma Road, Development Zone, Dalian, China
MN Pharmaceuticals
Tel:+90 212 337 3800
Address: 34349 Gayrettepe Istanbul - TURKEY
ZHEJIANG XINHUA PHARMACEUTICAL CO., LTD.
Tel:+86-576-85588383
Address: Linhai Zone, Linhai, Zhejiang, China
Jingdezhen Fuxiang Pharmaceutical Co.,Ltd.
Tel:
Address: No.53 Porcelain Town Arenue, Jingdezhen City, Jiangxi Province,China

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