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Tazobactam cas no:89786-04-9

Synonyms: (2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide; 2b-[(1,2,3-triazol-1-yl)methyl]-2a-methylpenam-3a-carboxylic acid 1,1-dioxide; Tazobactam acid; (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;

Identification
NameTazobactam
CAS89786-04-9
Synonyms(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide; 2b-[(1,2,3-triazol-1-yl)methyl]-2a-methylpenam-3a-carboxylic acid 1,1-dioxide; Tazobactam acid; (2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;
Molecular FormulaC10H12N4O5S
Molecular Weight300.29
Chemical Properties
AppearanceWhite or off-white powder
refractive index1.817
storage tempStore at?0-5°C
Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

Hazard Codes:?IrritantXi
Risk Statements: 36/37/38?
R36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36: Wear suitable protective clothing


Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous > 5gm/kg (5000mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

KIDNEY, URETER, AND BLADDER: HEMATURIA
Journal of Toxicological Sciences. Vol. 19(Suppl,
mouse LD50 intraperitoneal > 5gm/kg (5000mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Toxicological Sciences. Vol. 19(Suppl,
mouse LD50 intravenous > 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Toxicological Sciences. Vol. 19(Suppl,
mouse LD50 oral > 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Journal of Toxicological Sciences. Vol. 19(Suppl,
mouse LD50 subcutaneous > 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Journal of Toxicological Sciences. Vol. 19(Suppl,
rat LD50 intraperitoneal > 5gm/kg (5000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Journal of Toxicological Sciences. Vol. 19(Suppl,
rat LD50 intravenous > 5gm/kg (5000mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Toxicological Sciences. Vol. 19(Suppl,
rat LD50 oral > 5gm/kg (5000mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Journal of Toxicological Sciences. Vol. 19(Suppl,
rat LD50 subcutaneous > 5gm/kg (5000mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
Journal of Toxicological Sciences. Vol. 19(Suppl,

low toxicity--DL50 i.p. in mice over 4,000 mg/kg

supplier list

Nanjing Bangnuo Biotechnology Co., Ltd
Tel:86-1732-7098554
Address: shuanglong road,jiangning, nanjing,jiangsu
Hubei XinRunde Chemical Co., Ltd
Tel:86-27-83214668
Address: East and West Lake District, Wuhan, China
Hubei XinRunde Chemical Co., Ltd
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Address: East and West Lake District, Wuhan, China
Wuhan Dahua Weiye Pharmaceutical Co.,Ltd
Tel:86-27-59335372
Address: daijiashan 45,jiangan economic departmen zone,wuhan,hubei,China
Wuhan Dahua Weiye Pharmaceutical Co.,Ltd
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Address: daijiashan 45,jiangan economic departmen zone,wuhan,hubei,China
Hangzhou J&H Chemical Co., Ltd
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Zhejiang Haiqiang Chemical Co.,Ltd.
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Wuhan Fortuna Chemical Co., Ltd.
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HEBEI CUI FENG IMPORT&EXPORT TRADE CO.,LTD
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Boc Sciences
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Amadis Chemical Co.,Ltd.
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Address: SaiBo Pioneer Park.No.168,Jianding Road,Jianggan District.
AOPHARM
Tel:86-311-66600578
Address: C-2103 Wonder Business Square, 15 Yuhua West Rd.
Nanjing Chemlin Chemical Co., Ltd.
Tel:86-25-83697070
Address: Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China
Shijiazhuang Sdyano Fine Chemical Co., Ltd
Tel:86-311-80800737
Address: Room 37-2-2501, Yiyuan Dong Gang Jianshe Nan Stree
Wujiang Yingchuang Chemical Co., Ltd.
Tel:+86-(25)-8645 8768
Address: 215 Ying Tian Da Street, JianYe, Nanjing, Jiangsu 210017,

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