dog |
LDLo |
unreported |
120mg/kg (120mg/kg) |
|
"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. |
man |
LDLo |
oral |
157mg/kg (157mg/kg) |
behavioral: somnolence (general depressed activity) gastrointestinal: "hypermotility, diarrhea" gastrointestinal: nausea or vomiting |
Southern Medical Journal. Vol. 75, Pg. 1269, 1982. |
man |
TDLo |
oral |
1333mg/kg (1333mg/kg) |
behavioral: coma |
Human Toxicology. Vol. 1, Pg. 373, 1982. |
mouse |
LD50 |
oral |
68mg/kg (68mg/kg) |
behavioral: excitement behavioral: muscle weakness lungs, thorax, or respiration: dyspnea |
Proceedings of the Society for Experimental Biology and Medicine. Vol. 77, Pg. 269, 1951. |
mouse |
LD50 |
subcutaneous |
58mg/kg (58mg/kg) |
behavioral: excitement lungs, thorax, or respiration: dyspnea behavioral: muscle weakness |
Proceedings of the Society for Experimental Biology and Medicine. Vol. 77, Pg. 269, 1951. |
rat |
LD50 |
intraperitoneal |
15mg/kg (15mg/kg) |
|
Proceedings of the Society for Experimental Biology and Medicine. Vol. 113, Pg. 124, 1963. |
rat |
LD50 |
parenteral |
25mg/kg (25mg/kg) |
peripheral nerve and sensation: flaccid paralysis without anesthesia (usually neuromuscular blockage) behavioral: muscle contraction or spasticity) |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 84, Pg. 68, 1950. |
rat |
LD50 |
subcutaneous |
18mg/kg (18mg/kg) |
behavioral: excitement behavioral: muscle weakness lungs, thorax, or respiration: dyspnea |
Proceedings of the Society for Experimental Biology and Medicine. Vol. 77, Pg. 269, 1951. |
women |
LDLo |
oral |
6mg/kg (6mg/kg) |
behavioral: ataxia lungs, thorax, or respiration: respiratory stimulation gastrointestinal: nausea or vomiting |
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 482, 1969. |
women |
TDLo |
oral |
80mg/kg (80mg/kg) |
sense organs and special senses: conjunctive irritation: eye vascular: bp lowering not characterized in autonomic section |
Clinical Toxicology. Vol. 18, Pg. 973, 1981. |