9002-04-4|ThrombinProducts Supply - Chemical intermediates Network

Thrombin cas no:9002-04-4

Synonyms: Blood-coagulationfactor II, activated; Blood-coagulation factor IIa; E.C. 3.4.21.5; E.C.3.4.4.13; Factor IIa; Thrombase; Thrombin JMI; Thrombin-C; Thrombinar;Thrombofort; Thrombostat; Topical; Tropostasin

Identification

NameThrombin
CAS9002-04-4
SynonymsBlood-coagulationfactor II, activated; Blood-coagulation factor IIa; E.C. 3.4.21.5; E.C.3.4.4.13; Factor IIa; Thrombase; Thrombin JMI; Thrombin-C; Thrombinar;Thrombofort; Thrombostat; Topical; Tropostasin
EINECS(EC#)232-648-7
Molecular Formula C₆H₁₄O₆
Molecular Weight0

Chemical Properties

AppearanceWhite powder.
storage temp−20°C

Safety Data

Hazard Xn: Harmful;
Risk R36/37/38
Safety

A poison by intravenous route. Low toxicity by skin contact. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors.Safety information of Thrombin (CAS NO.9002-04-4):
Hazard Codes Harmful Xn, Biohazard B
Risk Statements
36/37/38 Irritating to eyes, respiratory system and skin
42 May cause sensitization by inhalation
Safety Statements
22 Do not breathe dust
24/25 Avoid contact with skin and eyes
36/37 Wear suitable protective clothing and gloves
WGK Germany 2
RTECS XO8950000
HS Code 30021099

HS Code 30021099

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	> 50mL/kg (50mL/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 329, 1984.
mouse	LD50	intravenous	7771ug/kg (7.771mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) KIDNEY, URETER, AND BLADDER: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 16, Pg. 669, 1988.
mouse	LD50	skin	> 3gm/kg (3000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA SKIN AND APPENDAGES (SKIN): HAIR: OTHER	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 1, Pg. 272, 1973.
mouse	LD50	subcutaneous	> 50mL/kg (50mL/kg)		Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 329, 1984.
rat	LD50	intraperitoneal	> 40mL/kg (40mL/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION	Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 329, 1984.
rat	LD50	subcutaneous	> 40mL/kg (40mL/kg)		Oyo Yakuri. Pharmacometrics. Vol. 28, Pg. 329, 1984.

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Thrombin cas no:9002-04-4

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