Luteinizing hormone cas no:9002-67-9

NameLuteinizing hormone
CAS9002-67-9
SynonymsICSH;Interstitial cell-stimulating hormone; LH; LH (hormone); Luteinising hormone;Luteinizing gonadotropic hormone; Luteotropic hormone; Luteotropin; Luteoziman;Lutogen; Lutropin; NIH-LH-B 9; PLH; Pituitary luteinizing hormone
EINECS(EC#)232-661-8
Molecular Weight30,000

Appearancelyophilized powder
storage temp2-8°C

Hazard T: Toxic;
Risk R60
Safety

The Hazard Codes of Luteinizing Hormone (CAS NO.9002-67-9):T
Risk Statements: R60:May impair fertility. 
Safety Statements: S53:Avoid exposure - obtain special instructions before use. S22:Do not breathe dust. S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 3
RTECS: OK6367000
Experimental reproductive effects.

The Health hazard data of Luteinizing Hormone (CAS NO.9002-67-9): 
Test type:TDLo - Lowest published toxic dose
Route of exposure:Subcutaneous
Test Species:Rodent - ratDOSE : 500 ug/kgSEX/DURATION : female 12 day(s) after conception
Toxicity:Reproductive - Maternal Effects - parturition
Reference:ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21203) V.1- 1917- Volume(issue)/page/year: 86,874,1970

Test type:TDLo - Lowest published toxic dose
Route of exposure:Subcutaneous
Test Species:Rodent - ratDOSE : 1375 ug/kgSEX/DURATION : female 12-22 day(s) after conception
Toxicity:Reproductive - Effects on Newborn - stillbirth
Reference:ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21203) V.1- 1917- Volume(issue)/page/year: 86,874,1970

Test type:TDLo - Lowest published toxic dose
Route of exposure:Subcutaneous
Test Species:Rodent - ratDOSE : 1 gm/kgSEX/DURATION : female 8 day(s) after conception
Toxicity:Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Fertility - abortion
Reference:PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 147,823,1974

Test type:TDLo - Lowest published toxic dose
Route of exposure:SubcutaneousRodent - ratDOSE : 219 ug/kgSEX/DURATION : female 13-16 day(s) after conception
Test Species:Reproductive - Maternal Effects - other effects
Toxicity:Reproductive - Maternal Effects - other effects
Reference:JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 85,51,1989

Test type:TDLo - Lowest published toxic dose
Route of exposure:Parenteral
Test Species:Rodent - ratDOSE : 12 gm/kgSEX/DURATION : male 6 day(s) pre-mating
Toxicity:Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
Reference:ANREAK Anatomical Record. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1906/08- Volume(issue)/page/year: 65,261,1936

Test type:TDLo - Lowest published toxic dose
Route of exposure:Intravenous
Test Species:Rodent - rabbitDOSE : 25 ug/kgSEX/DURATION : female 11 day(s) after conception
Toxicity:Reproductive - Fertility - other measures of fertility
Reference:JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 17,183,1968

Test type:TDLo - Lowest published toxic dose
Route of exposure:Intravenous
Test Species:Rodent - rabbitDOSE : 25 ug/kgSEX/DURATION : female 9 day(s) after conception
Toxicity:Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
Reference:ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21203) V.1- 1917- Volume(issue)/page/year: 77,337,1965