9005-49-6|HeparinProducts Supply - Chemical intermediates Network

Heparin cas no:9005-49-6

Synonyms: Ardeparin;AVE 5026;Centaxarin;CY 222;CY 216;Bemiparin;Arteven;Multiparin;Nadroparin;Nadroparine;Novoheparin;OP 386;OP 622;Octaparin;Pabyrn;Parnaparin;Reviparin;Subeparin;Tinzaparin;Vetren;a-Heparin;LipoHep Forte;KB 101;Heparin sulfate;Hapacarin;H 5284;Fraxiparin;Fragmin A;F 202;Clivarine;Clevarin;Mono-embolex;

Identification

NameHeparin
CAS9005-49-6
SynonymsArdeparin;AVE 5026;Centaxarin;CY 222;CY 216;Bemiparin;Arteven;Multiparin;Nadroparin;Nadroparine;Novoheparin;OP 386;OP 622;Octaparin;Pabyrn;Parnaparin;Reviparin;Subeparin;Tinzaparin;Vetren;a-Heparin;LipoHep Forte;KB 101;Heparin sulfate;Hapacarin;H 5284;Fraxiparin;Fragmin A;F 202;Clivarine;Clevarin;Mono-embolex;
EINECS(EC#)232-681-7
Molecular FormulaUnspecified
Molecular Weight402.65294

Chemical Properties

Appearancewhite or category of white crystalline powder.
refractive index1.711
storage tempKeep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Safety Data

Hazard May cause internal bleeding.
Safety

Safety Statements of Heparin (CAS NO.9005-49-6): 24/25
S24/25: Avoid contact with skin and eyes.
WGK Germany: 2
RTECS: MI0850000
F: 3-10
Moderately toxic by ingestion, intraperitoneal, and intravenous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x. See also HEPARIN SODIUM

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
man	TDLo	intravenous	3536units/kg/ (3536units/kg)		Southern Medical Journal. Vol. 80, Pg. 1450, 1987.
man	TDLo	subcutaneous	1857units/kg/ (1857units/kg)	CARDIAC: OTHER CHANGES	Southern Medical Journal. Vol. 80, Pg. 1450, 1987.
mouse	LD50	intraperitoneal	1900mg/kg (1900mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS	Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 60, Pg. 507, 1964.
mouse	LD50	intravenous	500mg/kg (500mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1366, 1986.
mouse	LD50	subcutaneous	500mg/kg (500mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS	Arzneimittel-Forschung. Drug Research. Vol. 36, Pg. 1366, 1986.
rat	LD50	oral	1950mg/kg (1950mg/kg)		German Offenlegungsschrift Patent Document. Vol. #2636091,
rat	LDLo	intraperitoneal	420mg/kg (420mg/kg)		Toxicology and Applied Pharmacology. Vol. 1, Pg. 156, 1959.
women	TDLo	subcutaneous	30uL/kg/5D-I (0.03mL/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	British Journal of Haematology. Vol. 82, Pg. 620, 1992.
women	TDLo	subcutaneous	48mg/kg/20D-I (48mg/kg)	BLOOD: HEMORRHAGE SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Australian and New Zealand Journal of Medicine. Vol. 28, Pg. 59, 1998.
women	TDLo	subcutaneous	1000units/kg/ (1000units/kg)		Southern Medical Journal. Vol. 80, Pg. 1450, 1987.

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Heparin cas no:9005-49-6

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