| dog |
LD50 |
oral |
> 2gm/kg (2000mg/kg) |
|
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 362, 1989. |
| mouse |
LD50 |
intramuscular |
1353mg/kg (1353mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
BLOOD: CHANGES IN SPLEEN |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 362, 1989. |
| mouse |
LD50 |
intravenous |
572mg/kg (572mg/kg) |
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
KIDNEY, URETER, AND BLADDER: OTHER CHANGES |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 362, 1989. |
| mouse |
LD50 |
subcutaneous |
2637mg/kg (2637mg/kg) |
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 362, 1989. |
| mouse |
LDLo |
oral |
> 5gm/kg (5000mg/kg) |
|
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 362, 1989. |
| rabbit |
LD50 |
oral |
> 3gm/kg (3000mg/kg) |
|
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 362, 1989. |
| rat |
LD50 |
intravenous |
700mg/kg (700mg/kg) |
KIDNEY, URETER, AND BLADDER: OTHER CHANGES |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 362, 1989. |
| rat |
LDLo |
intramuscular |
1gm/kg (1000mg/kg) |
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
KIDNEY, URETER, AND BLADDER: OTHER CHANGES |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 362, 1989. |
| rat |
LDLo |
oral |
5gm/kg (5000mg/kg) |
BEHAVIORAL: FOOD INTAKE (ANIMAL) |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 362, 1989. |
| rat |
LDLo |
subcutaneous |
4gm/kg (4000mg/kg) |
SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 20, Pg. 362, 1989. |
