90357-06-5|BicalutamideProducts Supply - Chemical intermediates Network

Bicalutamide cas no:90357-06-5

Synonyms: (2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methyl-propanamide;Casodex;Propanamide, N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)sulfonyl)-2-hydroxy-2-methyl-, (+-)-;Bicalutamide (JAN/USP);Casodex (TN);(±)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-methyl-[(4- fluorophenyl) sulfonyl]-2-hydroxy- 2-methyl propanamide;N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-fluorophenylsulfonyl)-2-hydroxy-2-methylpropanamide;Bicalutamide [USAN:BAN:INN];ICI 176334;Propanamide,N-[4-cyano-3-(trifluoromethyl)- phenyl]-3-[(4-fluorophenyl)sulfonyl]-2- hydroxy-2-methyl-;

Identification

NameBicalutamide
CAS90357-06-5
Synonyms(2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methyl-propanamide;Casodex;Propanamide, N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)sulfonyl)-2-hydroxy-2-methyl-, (+-)-;Bicalutamide (JAN/USP);Casodex (TN);(±)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-methyl-[(4- fluorophenyl) sulfonyl]-2-hydroxy- 2-methyl propanamide;N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(4-fluorophenylsulfonyl)-2-hydroxy-2-methylpropanamide;Bicalutamide [USAN:BAN:INN];ICI 176334;Propanamide,N-[4-cyano-3-(trifluoromethyl)- phenyl]-3-[(4-fluorophenyl)sulfonyl]-2- hydroxy-2-methyl-;
Molecular FormulaC₁₈H₁₄F₄N₂O₄S
Molecular Weight430.373373

Chemical Properties

Appearanceoff-white crystalline solid
refractive index1.577
storage tempStore in original container in a cool dark place.

Globally Harmonized System of Classification adn Labelling of Chemicals(GHS)

Hazardclass9

Safety Data

Hazard Xi: Irritant;
Risk R36/37/38
Safety

?Bicalutamide (CAS NO.90357-06-5) is?contraindicated ,females and children? must not be given to any patient who has shown a hypersensitivity reaction to its use.?
Hazard Codes:? Irritant Xi
Risk Statements: 36/37/38?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
?S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.
RIDADR: 3077
HazardClass: 9
PackingGroup: III

HS Code 29242995

Toxicity

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD	oral	> 2gm/kg (2000mg/kg)	?	Journal of Toxicological Sciences. Vol. 22, Pg. 75, 1997.
mouse	LD	oral	> 2gm/kg (2000mg/kg)	?	Journal of Toxicological Sciences. Vol. 22, Pg. 75, 1997.
mouse	LD50	intraperitoneal	> 2gm/kg (2000mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 42, Pg. 197, 2000.
rabbit	LD50	oral	> 200mg/kg (200mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 42, Pg. 197, 2000.
rat	LD	oral	> 2gm/kg (2000mg/kg)	?	Journal of Toxicological Sciences. Vol. 22, Pg. 75, 1997.
rat	LD50	intraperitoneal	> 2gm/kg (2000mg/kg)	?	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 42, Pg. 197, 2000.

supplier list

Ancheng Pharma Limited: Tel:+86-755-82713308; Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China

Aliapharm: Tel:+49 69 971412-0; Address: AliaPharm GmbH Frankfurt Niedenau 49 60325 Frankfurt / Main

Chemfar Ltd.: Tel:; Address: 16E,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China

Levachem Co. Ltd.: Tel:86-25-83247442 / 443 / 445 / 446 / 447; Address: 2112, SuNing Universal Mansion, 188 Guangzhou Road, Nanjing-210024, China

YANN PHARMACHEM: Tel:; Address: ROOM 506, BLOCK A 311 SIPING ROAD, SHANGHAI CHINA

Kingreat Chemistry Co.,Ltd.: Tel:; Address: Suite E, 14/F.,Jinyuan Plaza, 57 Hubin Road(S), Xiamen China

FAITH EAGLE (LABORATORY) LTD.: Tel:(+86-755) 82851290; Address: 15A/F.,Block A,World Trade Plaza,8# FuHong Rd., FuTian,Shenzhen, China

Shanghai bio-uchem I/E Co., Ltd.: Tel:; Address: 15/FRoom E No .1381-1383 Dong Fang Rd.Pu Dong.Shanghai,China

BRITIDE LIMITED: Tel:+86-571-86946005; Address: Room1307, Building 1, Baiyun Mansion, No.176, Tiancheng Road Hangzhou, China

J.INC.: Tel:+91 79 30903703; Address: 303, 3rd Floor, Royale Manor, Law Garden,Ellisbridge, Ahmedabad - 380006,Gujarat, India

Epochem Co., Ltd.: Tel:+86-(21)-6760-1595; Address: Building No 7, Xinfei Road 1500, Songjiang Industrial Zone, Songjiang, Shanghai 201611,

Genatal Life Science Ltd.: Tel:+86-(21)-54302195; Address: No.258, South HeHua Road, Shanghai,

Qilong Chemical Co., Ltd.: Tel:86-574-63858500; Address: No.586, Jiangnan Road,High-tech Park, Ningbo, Zhejiang 315040,

Kekule Pharma Limited: Tel:+91-(40)-23736150; Address: A4 Madhura Nagar Colony, S.R. Nagar, Hyderabad, Andhra Pradesh 500 038,

Sairam Organics Pvt. Ltd.: Tel:+91-(40)-23750123; Address: 102, Doyen chambers, Behind Saradhi studios, Ameerpet, Hyderabad, Andhra Pradesh 500073,

Bicalutamide cas no:90357-06-5

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