Proteinase,Streptomyces griseus cas no:9036-06-0

NameProteinase,Streptomyces griseus
CAS9036-06-0
SynonymsEmpynasePD; Pronase; Pronase A; Pronase E; Protease type XIV; Proteline; Protenaza 1;Streptomyces griseus protease; Streptomyces griseus proteinase; Type XIVprotease
EINECS(EC#)232-966-6
Molecular Formula C₁₉H₄₂BrN
Molecular Weight364.44748

Appearanceslightly brown powder
storage temp2-8°C

Hazard Xn: Harmful;
Risk R36/37/38
Safety

Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion.
Safety Information of Pronase (9036-06-0):
Hazard Codes: Xn
Risk Statements: 36/37/38-42
36/37/38: Irritating to eyes, respiratory system and skin 
42: May cause sensitization by inhalation 
Safety Statements: 22-24-26-36/37-24/25
22: Do not breathe dust 
24: Avoid contact with skin 
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
36/37: Wear suitable protective clothing and gloves 
24/25: Avoid contact with skin and eyes 
WGK Germany: 1
RTECS: UK9540000

1.		orl-rat LD50:3290 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),730.
2.		ipr-rat LD50:16,200 µg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),730.
3.		scu-rat LD50:100 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),730.
4.		ivn-rat LD50:15,800 µg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),730.
5.		orl-mus LD50:4010 mg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),730.
6.		ipr-mus LD50:14,100 µg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),730.
7.		scu-mus LD50:26,800 µg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),730.
8.		ivn-mus LD50:20,500 µg/kg		NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),730.