REPTILASE cas no:9039-61-6

NameREPTILASE
CAS9039-61-6
SynonymsE.C. 3.4.21.29;Reptilase R;Proteinase,Bothrops atrox serine;Batroxobin;VenomsBothrops jararaca Proteinase,Bothrops atrox serine;Defibrase;BothropaseSee;BOTROPASE;DEFIBRASE R;BOTHROPS VENOM PROTEINASE;DF-521;
EINECS(EC#)232-918-4

Safety

 Reptilase (CAS NO.9039-61-6) is a deadly poison by intravenous route. An experimental teratogen. Experimental reproductive effects.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	380ug/kg (0.38mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Oyo Yakuri. Pharmacometrics. Vol. 25, Pg. 339, 1983.
mouse	LD50	intravenous	384ug/kg (0.384mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Oyo Yakuri. Pharmacometrics. Vol. 25, Pg. 339, 1983.
rat	LD50	intravenous	210ug/kg (0.21mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Oyo Yakuri. Pharmacometrics. Vol. 25, Pg. 339, 1983.